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Year:2004
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Displaying 1 – 25 of 90 Awards
Company: Agave BioSystems, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 2
Abstract: DESCRIPTION (provided by applicant): Fluorescent semiconductor nanocrystals or quantum dots have many properties that make them superior to traditional dyes as fluorescent markers. Quantum dots have higher extinction coefficients making them brighter than traditional dyes (up to 1000 times brighter… more
Company: Agave BioSystems, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2004 / 1
Abstract: In this Phase I, Agave BioSystems proposes a novel approach for the development of a rapid and sensitive detection system for arsenic in drinking water based on the bioluminescent protein aequorin. The simplicity and ruggedness of this technology has the potential for providing low cost, on-line,… more
Company: Agave BioSystems, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2004 / 1
Abstract: Current technologies for marking of landing zones as well as areas for search and rescue have significant drawbacks ranging from the additional weight of batteries for some systems to plastic and metallic debris left behind. There are clear advantages both operationally and environmentally to… more
Company: Agave BioSystems, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2004 / 2
Abstract: Because many chemical and biological toxins selectively target respiratory endothelial cells, a biosensor using these cells in combination with Electric Cell-substrate Impedance Sensing (ECIS) technology has many useful applications for detection and early warning monitoring of a broad range of… more
Company: Agave BioSystems, Inc. Agency/Program/Year/Phase: NASA / SBIR / 2004 / 1
Abstract: Due to the extensive amounts of data generated from the genome sequencing projects, the focus of genomics has shifted from elucidating DNA sequence to the interpretation of gene function. In addition, as proteins are most often the targets of drugs, a method of studying the genome at the protein… more
Company: Agave BioSystems, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2004 / 1
Abstract: Because endothelial cells organize to form a tight barrier under normal conditions, several electrical devices have been used to measure the electrical resistance of endothelial cell monolayers. An Electric Cell-substrate Impedance Sensing (ECIS) system can measure the electrical impedance of… more
Company: Agave BioSystems, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): In response to the solicitation for development of nanotechnologies to improve cancer diagnosis by NCI, Agave BioSystems, in collaboration with Dr. George Malliaras, of the Department of Materials Science and Engineering at Cornell University, proposes to… more
Company: Agave BioSystems, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): Despite numerous advances in high throughput screening (HTS) and system automation, the identification of specific ligands remains time consuming and resource intensive. A major obstacle to more efficient screening of potential ligands is the current… more
Company: Agave BioSystems, Inc. Agency/Program/Year/Phase: DOD / STTR / 2004 / 1
Abstract: Cultured cell-based biosensors offer insight into the physiological action of the agent of interest, which is an advantage over other types of sensors. The development of cell-based biosensors that are field-portable would increase their utility in toxicology and environmental monitoring. One of… more
Company: AGENNIX, INC. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 2
Abstract: DESCRIPTION (provided by applicant): Research Objectives: Determine the safety, pharmacokinetics, pharmacodynamics, and efficacy of topical recombinant human lactoferrin (rhLF) in promoting healing in diabetic ulcers. There are 7.5 million US patients with chronic skin wounds with annual… more
Company: AGENNIX, INC. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION: Oral mucositis is a major dose-limiting toxic effect of intensive cancer chemotherapy and radiotherapy. In addition to the morbidity directly caused by severe oral mucositis, it can cause secondary morbidities by limiting oral intake or even lead to dose reduction or delay in further… more
Company: AGENNIX, INC. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): The purpose of this research is to extend work to determine the efficacy of orally administered recombinant human lactoferrin (rhLF) in an established primate model of asthma. Asthma is one of the most prevalent chronic inflammatory diseases in the United States… more
Company: AGENNIX, INC. Agency/Program/Year/Phase: HHS / STTR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): This feasibility study is based on our hypothesis that recombinant human lactoferrin [rhLF] can prevent or reduce severity of necrotizing enterocolitis [NEC]. NEC is mainly a disease of very low birth weight [VLBW] human infants. It is a leading cause of… more
Company: AMERICAN LIFE SCIENCE PHARMACEUTICALS Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): Pain is a serious, debilitating condition that is under-treated because of the dose-limiting side effects of currently used opiate drugs such as morphine. Enkephalin is an endogenous opiate peptide, which induces analgesia, but unlike morphine it has few, if any… more
Company: APPLIED MEDIA ANALYSIS, INC. Agency/Program/Year/Phase: DOD / SBIR / 2004 / 2
Abstract: Phase II of the MATES project will extend our current system for road sign detection, recognition and translation on handheld devices in several novel and innovative directions. Our core application will be document triage, where the soldier obtains a gist translation or keyword profile of a… more
Company: APPLIED MEDIA ANALYSIS, INC. Agency/Program/Year/Phase: NSF / SBIR / 2004 / 1
Abstract: This Small Business Innovation Research (SBIR) Phase II research project develops the concept of using hand-held, mobile devices to link the physical world to information networks using advanced pattern and symbol recognition technology that will be deployed on the mobile device. The proposed mobile… more
Company: Lickenbrock Technologies LLC Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): Fluorescence resonance energy transfer (FRET) imaging is a microscope technique that uses a dye pair. It detects bonding of proteins, and in turn, is used to deduce many activities such as chromosome dynamics through the cell cycle. When one dye (the donor),… more
Company: BENEFICIAL DESIGNS INC Agency/Program/Year/Phase: USDA / SBIR / 2004 / 1
Abstract: Currently, the benefits of objective trail information are limited in rural areas because the team of people required to complete the UTAP is difficult and costly to assemble. The USDA Forest Service is responsible for the management of 133,000 miles of trails and public lands with trails held by… more
Company: BEVILACQUA RESEARCH CORP. Agency/Program/Year/Phase: DOD / SBIR / 2004 / 2
Abstract: The overall goal of Phase II is to develop a powerful tool to correlate large amounts of asynchronous data in near real-time and meet current operational requirements for the Joint Command and Control Community for rapid, accurate Battle Damage Assessment and operational assessment. The team will… more
Company: BIOTECHNICAL COMMUNICATIONS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: N/A
Company: Concurrent Analytical, Inc. Agency/Program/Year/Phase: HHS / STTR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): The overall goal of this project is the development of a fully automated, wireless ethernet capable, near realtime, field deployable immunoassay-based analysis system for the concurrent, ultra low-level detection of biowarfare agents in air or water by using… more
Company: CYTEL SOFTWARE CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2004 / 2
Abstract: DESCRIPTION (provided by applicant): This is a Phase II SBIR proposal for completing the development of a comprehensive collection of statistical tools embedded in LogXact, in EGRET, in SAS as PROCs and in SPLUS as functions. This set of tools will compute maximum likelihood estimates for… more
Company: CYTEL SOFTWARE CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): This is a Phase I SBIR proposal for the development of computer software performing small sample exact inference for correlated categorical data. Such data are now common in many, biomedical areas of research, such as genetics, ophthalmology, and teratology. In… more
Company: Firehole Technologies, Inc. Agency/Program/Year/Phase: DOD / STTR / 2004 / 1
Abstract: Programs such as Airborne Laser and Space-Based Laser require highly mass efficient structures. Because of their high specific strength and stiffness this naturally leads to graphite fiber reinforced polymer (GFRP) materials for many system components. In fluid storage tank applications GFRP… more
Company: Forest Concepts, Llc Agency/Program/Year/Phase: USDA / SBIR / 2004 / 1
Abstract: Rural communities in forested areas need to thin small diameter trees from overstocked stands. The smallwood does not have adequate market demand to support the cost of collection and delivery. This project explores the opportunity to market more smallwood to retail customers and urban markets by… more
Displaying 1 – 25 of 90 Awards
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