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Proactive Methodology for Identifying Problem Aerospace Parts

Company: ANAUTICS, INC. Agency/Program/Year/Phase: DOD / SBIR / 2013 / 2
Abstract: ABSTRACT: The proposed solution would provide the United States Air Force (USAF) a thin client application for proactively identifying problem parts. Our solution is dependant on a digital Bill of Materials (BOM) which we also provide a tool for importing and loading the cleansed parts structure… more

ULTRA-HIGH PERFOMANCE SOLID-STATE REFRIGERATION USING II-VI LOW DIMENSIONAL STRUCTURE

Company: Amethyst Research Incorporated Agency/Program/Year/Phase: DOD / SBIR / 2013 / 1
Abstract: ABSTRACT: This program targets development of a high-performance thermoelectric (TE) cooler with a figure-of-merit, ZT>3, which greatly exceeds currently available technology. The cooler is fabricated using Group II-VI compound semiconductors, i.e. HgCdSe or HgCdTe, using a low dimensional… more

Detectors with Improved Near-to-Mid IR Performance and Reduced Cooling Requirements

Company: Amethyst Research Incorporated Agency/Program/Year/Phase: NASA / STTR / 2013 / 1
Abstract: This STTR Phase I proposal addresses a NASA need for improved near-to-mid IR detectors for imaging and spectroscopy. High performance IR detectors with cutoff wavelengths in the range of 2.5?5.0 microns will be developed using InGaAs / AlAsSb semiconductor materials. The proposal uses a two-pronged… more

Proactive Methodology for Identifying Problem Aerospace Parts

Company: VG Enterprises Inc. Agency/Program/Year/Phase: DOD / SBIR / 2013 / 2
Abstract: ABSTRACT: Accurate prediction of part performance/reliability is at the core of health management of air vehicles and of supply chain management. Methodologies are needed to accurately predict/evaluate parts performance/reliability with compounding problem criteria/factors for early corrective… more

ABLE Kids II - Advanced Biofidelic Lower Extremity Kids Prosthesis II

Company: Orthocare Innovations, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: DESCRIPTION (provided by applicant): The Advanced Biofidelic Lower Extremity Kids prosthesis (ABLE Kids) project will advance the state-of-the-art of pediatric prosthesis systems by advancing the demonstrably successful Phase I device and refining it intoan ultracompact and lightweight form factor… more

Computerized Orthotic Prescription System - COPS

Company: Orthocare Innovations, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: DESCRIPTION (provided by applicant): Stiffness and alignment of ankle-foot orthoses (AFOs) should be tuned optimally to maximize their function. Improperly tuned AFO may induce joint pain, reduced ambulatory function, and increased medical complications for patients with stroke. Therefore, the… more

Proactive Methodology for Identifying Problem Aerospace Parts

Company: ANAUTICS, INC. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: ABSTRACT: The engineer will be guided through the creation of criteria, alternatives and evaluation techniques in order to make a better decision. BENEFIT: The engineer will be guided through the creation of criteria, alternatives and evaluation techniques in order to make a better decision.

Multi-Attribute Reliability and Maintainability Engineering Assessment Methodology

Company: ANAUTICS, INC. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 2
Abstract: ABSTRACT: As we move from a paper-based world into a digital environment, the internet will soon evolve from a virtual documentation system into a vibrant ecosystem of data where documents and human actors play an even smaller role. We are currently reaching a tipping point in history concerning… more

Development of an Alternative Screening Method for Detecting Evidence of Mycobacterium Tuberculosis Infections

Company: Bijhem Scientific Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: This Small Business Innovation research Phase I proposes the development of a practical and reliable in-vitro test for detecting the evidence of Mycobacterium tuberculosis (MTB) infection as an alternative to the tuberculin skin test (PPD-TST) and to the interferon gamma release assays (IGRAs). The… more

A Small Molecule Targeting Wnt Pathway for Treatment of Diabetic Retinopathy

Company: CHARLESSON, LLP Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Diabetic retinopathy (DR) is a common complication of diabetes and a leading cause of blindness. This sight-threatening condition has become a public health challenge in the US. Currently, there is no FDA- approved drugfor DR. Laser photocoagulation has remained… more

Identifying the drug target in dormant cancer cells

Company: DORMATARG, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): In spite of billions of dollars spent in the War on Cancer, cancer-specific mortality has changed little as a result, and the vast majority of cures are produced surgically, not from chemotherapy. The main problem is that even with early detection; most cancers… more

Development of an Anti-P-selectin Antibody for the Treatment of Sickle Cell Disea

Company: SELEXYS PHARMACEUTICALS CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: DESCRIPTION (provided by applicant): Selexys Pharmaceuticals is developing a humanized monoclonal antibody drug called SelG1 directed against P-selectin for the treatment of vasoocclusive crisis in patients with sickle cell disease. The ultimate goal of this Phase IIB proposal is to further advance… more

Defect Passivation for Improved Material Properties in Ga-free and Ga-based SLS

Company: Amethyst Research Incorporated Agency/Program/Year/Phase: DOD / STTR / 2012 / 1
Abstract: A collaboration between Amethyst Research Inc., University Multispectral Laboratories (a government-owned, contractor-operated nonprofit corporation), and Teledyne Imaging Systems (a large defense contractor) proposes to develop/improve high-performance infrared sensors based on Type II,… more

The Use of Hydrogen for Defect Reduction in Large Format Infrared Detector Materials

Company: Amethyst Research Incorporated Agency/Program/Year/Phase: DOD / STTR / 2012 / 2
Abstract: In Phase I we demonstrated a novel in-situ cleaning technique based on UV-activated surface reactions involving ozone and hydrogen to remove organic adsorbates and chemically-bonded impurities, e.g oxides, from the substrate surface. In Phase II the program will develop this process to… more

Low Dark Current, Extended Wavelength SWIR Sensors Using Hydrogenated nBn InGaAs

Company: Amethyst Research Incorporated Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: Improved performance SWIR sensors with extended wavelength response to 2.5 microns will be developed using two disruptive technologies with which Amethyst has demonstrated success: nBn detector structures and defect passivation via hydrogenation. Similar to conventional extended wavelength… more

Antigen Immunoassay for Diagnosis of Coccidioidomycosis

Company: Immuno-Mycologics INC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Coccidioidomycosis, also known as Valley Fever, is a fungal disease caused by Coccidioides spp. that infects an estimated 150,000 people each year in the United States. Current diagnosis of coccidioidomycosis relieson detection of anti-coccidioidal antibodies… more

Point-of-care immunoassay for diagnosis of cryptococcosis in HIV/AIDS from whole blood

Company: Immuno-Mycologics INC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: Cryptococcal meningitis (CM) kills more than 600,000 HIV-infected individuals globally per year, with the highest yearly incidence occurring in sub-Saharan Africa. There is a critical need for a simple diagnostic tool for cryptococcosis that can be used in resource-limited countries. An innovative… more

High Pressure Open Channel Electroosmotic Pump

Company: Microchem Solutions Agency/Program/Year/Phase: DOE / STTR / 2012 / 2
Abstract: The objective of lab-on-chip (LOC) is to integrate and perform multiple analytical processes on a microchip platform. So far, most LOC research has been focused on electrophoretic separations. Limited progress has been made on multi-process integration, due mainly to the lack of a robust and… more

Development of a Miniature Right Heart Support Device

Company: VADovations, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Congestive heart failure (CHF) is one of the most serious medical challenges of our day. With 5 million Americans compromised by the ravages of this disabling disease, CHF is the leading cause of Medicare hospital admissions. The economic burden exceeds 40… more

SBIR Phase I: Efficient structural mass from microstructural design

Company: MetCel LLC Agency/Program/Year/Phase: NSF / SBIR / 2012 / 1
Abstract: This Small Business Innovation Research Phase I project proposes high specific strength composite sandwich panels using a new form of manufacturing, tailored for Amorphous Metal Honeycomb (AMH) cores. Previously it was impossible to form these alloys as honeycombs since they do not behave like… more

Proactive Methodology for Identifying Problem Aerospace Parts

Company: VG Enterprises Inc. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: ABSTRACT: This proposal proposes to develop an agile methodology to identify bad actor parts to proactively address part performance. The methodology with algorithms and models will be developed by merging ideas from different areas of Science and Engineering. Some of the algorithms and models to… more

Terahertz Nondestructive Evaluation and Characterization of Missile Radomes

Company: Wavetech, LLC Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: We propose to demonstrate the feasibility of using time domain terahertz measurements to locate, identify and image defects and material variations within advanced composite materials used in missile radomes. We will investigate the time and frequency domain transmission properties of radome… more

Development HMTD-Containing Porous Materials as Non-Detonable Training Aids for Canines

Company: XploSafe LLC Agency/Program/Year/Phase: DHS / SBIR / 2011 / 2
Abstract: The current practice of training canines for explosives detection utilizing actual explosives requires qualified personnel that are trained to handle explosive materials making the training both manpower-intensive and costly. The expense is further exacerbated by the need to handle and dispose… more

Development of Microarrays-based Metagenomics Technology for Monitoring Sulfate-Reducing Bacteria in Subsurface Environments

Company: Glomics, Inc Agency/Program/Year/Phase: DOE / STTR / 2011 / 2
Abstract: Due to their vast diversity and as-yet uncultivated status, detecting, characterizing and quantifying microorganisms in natural settings are of grand challenge, and understanding the mechanistic linkages between microbial diversity and ecosystem functioning and their feedback responses to human… more

Development of Novel Random Network Theory-Based Approaches to Identify Network Interactions Among Nitrifying Bacteria

Company: Glomics, Inc Agency/Program/Year/Phase: DOE / STTR / 2011 / 2
Abstract: The interactions among different microbial populations in a community play critical roles in determining ecosystem functioning but very little is known about the network interactions in a microbial community due to the lack of appropriate experimental data and computational analytic tools.… more