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Development of a Novel IR Detector for Improved CO2 Subsurface Sequestration Monitoring

Company: Amethyst Research Incorporated Agency/Program/Year/Phase: DOE / SBIR / 2014 / 1
Abstract: Low cost and accurate monitoring of sequestered gases such as CO2 is critical to insure that sequestered gases are not reentering the atmosphere. Management requires, in part, improved atmospheric and ground monitoring of greenhouse gases through sensors capable of measuring the flux,… more

Low Dark Current, Extended Wavelength SWIR Sensors Using Hydrogenated Unipolar Barrier InGaAs

Company: Amethyst Research Incorporated Agency/Program/Year/Phase: DOD / SBIR / 2014 / 2
Abstract: In this Phase II program, improved performance SWIR sensors with extended wavelength response to 2.5 microns will be developed using two disruptive technologies, which Amethyst has successfully demonstrated in the Phase I program: unipolar barrier (e.g., nBn) detector structures, and defect… more

HIGH PRESSURE MONOLITH ELECTROOSMOTIC PUMP

Company: MicroChem Solutions Agency/Program/Year/Phase: DOE / STTR / 2014 / 2
Abstract: The objective of lab-on-chip (LOC) is to integrate and perform multiple analytical processes on a microchip platform. So far, most LOC research has been focused on electrophoretic separations. Limited progress has been made on multi-process integration, due mainly to the lack of a robust and… more

Multiple Mechanism (MULTIMECH) Body Armor

Company: TechVen Partners LLC Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: Body armor used today is an achievement of modern science, constructed of high tensile strength, manmade fibers and ultra hard, impervious ceramics. As impressive as this armor is, however, one of the most critical areas of armor testing methodology has remained largely unchanged from its National… more

Scale-Up of ATPE Technology to Produce Highly Enriched Semiconducting SWCNTs

Company: SouthWest NanoTechnologies (SWeNT) Agency/Program/Year/Phase: DOC / SBIR / 2014 / 1
Abstract: Single-walled carbon nanotubes (SWCNTs) have unique material properties making them very attractive for use in a variety of electronic applications. However, as-grown SWCNTs contain a mixture of tubes with heterogeneous optical and electronic properties. The chiral species must be separated in order… more

Proactive Methodology for Identifying Problem Aerospace Parts

Company: Anautics, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2013 / 2
Abstract: ABSTRACT: The proposed solution would provide the United States Air Force (USAF) a thin client application for proactively identifying problem parts. Our solution is dependant on a digital Bill of Materials (BOM) which we also provide a tool for importing and loading the cleansed parts structure… more

Developing A Novel Therapy for Diabetic Retinopathy

Company: CHARLESSON, LLP Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Diabetic retinopathy (DR) is a common complication of diabetes and a leading cause of vision loss in the United States. Unfortunately, there is no FDA-approved pharmacotherapy for DR. Current treatments in clinical practice and trails, such as laser… more

Expanding Precision Particle Fabrication Technology for the Widespread Control of

Company: TRANSTIMULATION RESEARCH, INC. Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Diabetes affects more than 8% of Americans and costs over 174 billion in 2007 in USA. Recently bariatric surgery, such as Roux-en-Y gastric bypass, has been proposed for treating diabetic patients with obesity due to its hypoglycemic effect on postprandial blood… more

ULTRA-HIGH PERFOMANCE SOLID-STATE REFRIGERATION USING II-VI LOW DIMENSIONAL STRUCTURE

Company: Amethyst Research Incorporated Agency/Program/Year/Phase: DOD / SBIR / 2013 / 1
Abstract: ABSTRACT: This program targets development of a high-performance thermoelectric (TE) cooler with a figure-of-merit, ZT>3, which greatly exceeds currently available technology. The cooler is fabricated using Group II-VI compound semiconductors, i.e. HgCdSe or HgCdTe, using a low dimensional… more

Detectors with Improved Near-to-Mid IR Performance and Reduced Cooling Requirements

Company: Amethyst Research Incorporated Agency/Program/Year/Phase: NASA / STTR / 2013 / 1
Abstract: This STTR Phase I proposal addresses a NASA need for improved near-to-mid IR detectors for imaging and spectroscopy. High performance IR detectors with cutoff wavelengths in the range of 2.5?5.0 microns will be developed using InGaAs / AlAsSb semiconductor materials. The proposal uses a two-pronged… more

Immunoassay for diagnosis of invasive fungal disease

Company: Immuno-Mycologics INC Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Early diagnosis of infectious disease is critical to patient outcome. An important early question is - is it a fungus, a bacterium or a virus? A rapid answer to this question would allow preemptive treatment that cansave lives. The goal of this project is a… more

Flow Cytometry Assay for Detection of Cryptococcal Antigen

Company: Immuno-Mycologics INC Agency/Program/Year/Phase: HHS / SBIR / 2013 / 2
Abstract: Cryptococcal meningitis (CM) kills more than 600,000 HIV-infected individuals globally per year, with the highest yearly incidence occurring in sub-Saharan Africa. There is a critical need for a simple diagnostic tool for cryptococcosis that can be used in resource-limited countries. An innovative… more

Development of a Miniature Right Heart Support Device

Company: VADOVATIONS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2013 / 2
Abstract: DESCRIPTION (provided by applicant): Congestive heart failure (CHF) is one of the most serious medical challenges of our day. With 5 million Americans compromised by the ravages of this disabling disease, CHF is the leading cause of Medicare hospital admissions. The economic burden exceeds 40… more

Selection-driven plant metabolites for treatment of CNS diseases

Company: COARE BIOTECHNOLOGY, INC. Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Pancreatic ductal adenocarcinoma (PDAC) is a solid tumor and is the fourth leading cause of cancer-related death in the U.S. The 5-year survival rate of its victims is lt5%. There is increasing evidence that most solidtumors have a subpopulation of… more

Proactive Methodology for Identifying Problem Aerospace Parts

Company: VG Enterprises Inc. Agency/Program/Year/Phase: DOD / SBIR / 2013 / 2
Abstract: ABSTRACT: Accurate prediction of part performance/reliability is at the core of health management of air vehicles and of supply chain management. Methodologies are needed to accurately predict/evaluate parts performance/reliability with compounding problem criteria/factors for early corrective… more

STTR Phase I: All-composite Storage for Adsorbed Natural Gas

Company: CleanNG LLC Agency/Program/Year/Phase: NSF / STTR / 2013 / 1
Abstract: This Small Business Technology Transfer Phase I project will create a fuel storage system for natural gas using adsorbent technology. This adsorbed natural gas (ANG) technology will allow this all-composite, conformable, lower pressure system to hold equivalent amounts of natural gas as… more

Medical Imaging Motion Monitor (MIMM)

Company: SENSIQ TECHNOLOGIES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION: Incremental improvements in label free screening technologies over the past decade have not produced the capability necessary to support the changing needs of drug discovery programs. Persistent artifacts related to non-specific binding, promiscuous binding, precipitation, complex… more

ABLE Kids II - Advanced Biofidelic Lower Extremity Kids Prosthesis II

Company: Orthocare Innovations, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: DESCRIPTION (provided by applicant): The Advanced Biofidelic Lower Extremity Kids prosthesis (ABLE Kids) project will advance the state-of-the-art of pediatric prosthesis systems by advancing the demonstrably successful Phase I device and refining it intoan ultracompact and lightweight form factor… more

Computerized Orthotic Prescription System - COPS

Company: Orthocare Innovations, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: DESCRIPTION (provided by applicant): Stiffness and alignment of ankle-foot orthoses (AFOs) should be tuned optimally to maximize their function. Improperly tuned AFO may induce joint pain, reduced ambulatory function, and increased medical complications for patients with stroke. Therefore, the… more

Proactive Methodology for Identifying Problem Aerospace Parts

Company: Anautics, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: ABSTRACT: The engineer will be guided through the creation of criteria, alternatives and evaluation techniques in order to make a better decision. BENEFIT: The engineer will be guided through the creation of criteria, alternatives and evaluation techniques in order to make a better decision.

Multi-Attribute Reliability and Maintainability Engineering Assessment Methodology

Company: Anautics, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 2
Abstract: ABSTRACT: As we move from a paper-based world into a digital environment, the internet will soon evolve from a virtual documentation system into a vibrant ecosystem of data where documents and human actors play an even smaller role. We are currently reaching a tipping point in history concerning… more

Development of an Alternative Screening Method for Detecting Evidence of Mycobacterium Tuberculosis Infections

Company: Bijhem Scientific Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: This Small Business Innovation research Phase I proposes the development of a practical and reliable in-vitro test for detecting the evidence of Mycobacterium tuberculosis (MTB) infection as an alternative to the tuberculin skin test (PPD-TST) and to the interferon gamma release assays (IGRAs). The… more

A Small Molecule Targeting Wnt Pathway for Treatment of Diabetic Retinopathy

Company: CHARLESSON, LLP Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Diabetic retinopathy (DR) is a common complication of diabetes and a leading cause of blindness. This sight-threatening condition has become a public health challenge in the US. Currently, there is no FDA- approved drugfor DR. Laser photocoagulation has remained… more

Identifying the drug target in dormant cancer cells

Company: DORMATARG, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): In spite of billions of dollars spent in the War on Cancer, cancer-specific mortality has changed little as a result, and the vast majority of cures are produced surgically, not from chemotherapy. The main problem is that even with early detection; most cancers… more

Development of an Anti-P-selectin Antibody for the Treatment of Sickle Cell Disea

Company: SELEXYS PHARMACEUTICALS CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: DESCRIPTION (provided by applicant): Selexys Pharmaceuticals is developing a humanized monoclonal antibody drug called SelG1 directed against P-selectin for the treatment of vasoocclusive crisis in patients with sickle cell disease. The ultimate goal of this Phase IIB proposal is to further advance… more