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Applications and Methods for Continuous Monitoring of Physiological Chemistry

Company: Pinnacle Technology, Inc. Agency/Program/Year/Phase: DOD / STTR / 2014 / 2
Abstract: Point of care (POC) diagnostic devices are a well established market but have significant growth opportunities. Stable off-the-shelf biological recognition elements available in a form that can be readily incorporated into POC devices will be essential for wide spread use and deployment. Other… more

Microstructured Semiconductor Neutron Detector Arrays for Neutron Scattering Measurements

Company: Radiation Detection Technologies, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2014 / 2
Abstract: There is a need for high-resolution, high-efficiency, and high-rate neutron imaging detectors at neutron scattering facilities. The Oak Ridge National Laboratory Spallation Neutron Source neutron scattering instruments the VULCAN Engineering Diffractometer, the TOPAZ Crystal… more

Portable Neutron Spectrometer

Company: Radiation Detection Technologies, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: ABSTRACT: Proposed is the development of an advanced solid state neutron spectrometer (NeuKopis) with directional resolve, building from prototype instruments that have demonstrated the art-of-the-possible. The intrinsic neutron detection efficiency of the refined BENEFITS: Low power, solid state,… more

Late Award - Field-Assembled Component-Based Rotor Blades

Company: Wetzel Engineering, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2014 / 2
Abstract: The utility-scale wind industry is evolving towards very large ( & gt;4MW) machines with blades longer than 70m for both land-based and off-shore installations. There is a rapid ramp in cost associated with ground transportation of blades longer than 65m, rising to a threshold that is… more

Fuel-Air Explosive Technologies from Dual-Use Materials

Company: Energetic Materials Research and Enginee Agency/Program/Year/Phase: DOD / SBIR / 2014 / 2
Abstract: ABSTRACT: In our Phase I SBIR work to date, we constructed an implosion system using carefully-designed components and geometries that reproducibly reacts nearly 100% of the JP10 in the test cell. Using ALE3D we have also been able to qualitatively describe the major hydrodynamic processes… more

3-D Smart Aircraft Conceptual Design Tool

Company: Design, Analysis and Reseach Corporation Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: ABSTRACT: Design, Analysis and Research Corporation (DARcorporation) proposes to develop a 3-D visualization and modification environment as well as higher fidelity modeling capability based on defined geometry to be incorporated into the Advanced Aircraft Analysis (AAA) software. AAA is a… more

Innovative Tactical Bulk Fuel Delivery System Restraint System

Company: Burchell Professional Group Inc Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: A new innovative tactical fuel bulk system restraint system concept was researched and developed. Analysis confirmed that this new restraint system met all military requirements.

Expanding Precision Particle Fabrication Technology for the Widespread Control of

Company: ORBIS BIOSCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2013 / 2
Abstract: DESCRIPTION (provided by applicant): A critical need currently exists in the pharmaceutical market for microparticles that can accurately and effectively control the release of poorly water-soluble compounds. Although these poorly water-soluble drugs areprojected to have high clinical efficacy,… more

Defect Passivation for High Performance HgCdTe on Si

Company: ARC Technology Agency/Program/Year/Phase: DOD / STTR / 2013 / 2
Abstract: The potential threat of directed energy weapons (DEW) and other high peak power electromagnetic transient signals require radar systems to implement front door protection against high power signals. Fast ultra wideband (UWB) and high power microwave (HPM) signals are not successfully blocked by… more

Electro-Optic Terminal Protection for Radar Systems Phase II

Company: ARC Technology Agency/Program/Year/Phase: DOD / STTR / 2013 / 2
Abstract: The potential threat of directed energy weapons (DEW) and other high peak power electromagnetic transient signals require radar systems to implement front door protection against high power signals. Fast ultra wideband (UWB) and high power microwave (HPM) signals are not successfully blocked by… more

Electrically Generated Haptic Feedback to Simulate Virtual Explosions - Phase II

Company: ARC Technology Agency/Program/Year/Phase: DOD / SBIR / 2013 / 2
Abstract: This proposal details the development of a variable pulsed power system and custom load that simulates the audio, visual, and tactile response of a variety of explosive devices. The system operates by tailoring the driver parameters, such as voltage and current discharge profile, through the… more

AirCore Reusable InSitu Sampler for CO2 and Trace Gas Measurements

Company: KALSCOTT Engineering, Inc. Agency/Program/Year/Phase: NASA / SBIR / 2013 / 1
Abstract: A novel design for an in situ air sampling sensor for CO2 and trace gases is proposed. The sensor, named AirCore, provides the advantages of existing in situ sensors (e.g. high resolution) but eliminates possible biases in analysis that often originate from imperfect measurement condition. The… more

Oral delivered bone building therapy for osteoporosis

Company: OSTEOGENEX, INC Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): The osteoporosis market is still in demand for new therapeutics due to the lack of safe orally available bone building drugs. Currently, parathyroid hormone (PTH; FORTEOTM) and its analogs are the only bone building therapies available yet they capture only 8% of… more

Simplifying fMRI Integration in the Cognitive Neurosciences

Company: PERCEPTION RESEARCH SYSTEMS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Over the last two decades, fMRI has evolved into a widely used technology in basic biobehavioral research. The user base for this technology continues to increase due to the growth of the field of cognitive neuroscience, and this increase is poised to accelerate… more

Enabling Mobile Device-Based Stimulus Presentation in Biobehavioral Research

Company: PERCEPTION RESEARCH SYSTEMS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): The ubiquity of high-performance mobile devices, such as smartphones and tablets, has the potential to significantly broaden and improve the methods of data collection used in the biobehavioral sciences. Contemporary mobile devices are capable of highly engaging… more

Group housing: A robotic system to track and interact with individuals

Company: PINNACLE TECHNOLOGY, INC Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Individually housing animals, even for a short period, is known to have a negative influence on behavior, learning ability, and physiology. Group-housed rodents are better able to cope with stress through improved behavioral and physiological responses.… more

A Nicotine Biosensor for Addiction Studies

Company: PINNACLE TECHNOLOGY, INC Agency/Program/Year/Phase: HHS / SBIR / 2013 / 2
Abstract: ABSTRACT Tobacco-related deaths cost the United States approximately 200 billion each year. Nicotine is singularly responsible for the dependence-forming properties of tobacco smoking and, once introduced to the body, affects the brain within 15 seconds.Breaking nicotine addiction is challenging… more

SBIR Phase I: Adaptive analog nonlinear circuits for improving properties of electronic devices

Company: Avatekh Inc. Agency/Program/Year/Phase: NSF / SBIR / 2013 / 1
Abstract: This Small Business Innovation Research (SBIR) Phase I project aims at developing advanced analog nonlinear algorithms and circuits for mitigation of in-band noise and interference, especially that of manmade origin, affecting various signals of interest and limiting the performance of the affected… more

STTR Phase I: Novel Peptide Hydrogel for 3D Cell Culture

Company: PepGel,LLC Agency/Program/Year/Phase: NSF / STTR / 2013 / 1
Abstract: This Small Business Technology Transfer (STTR) Phase I project aims to use a newly discovered peptide (h9e) hydrogel technology to provide an affordable and easy-to-use 3D cell culture system with high throughput screen and accurate in vivo representative. To bridge the fundamental understanding of… more

First Generation of Controlled-Release Bacteriocins/Anti-Microbials

Company: Orbis Biosciences, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2013 / 2
Abstract: Combat ration Intermediate Moisture (IM) products currently use low pH and water content (aw) to discourage bacterial growth. The long-term goal of this SBIR project is to maintain the microbial stability of IM ration components over a three-year shelf life while increasing the pH and aw values for… more

Microstructured Semiconductor Neutron Detector Arrays for Neutron Scattering Measurements

Company: Radiation Detection Technologies, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2013 / 1
Abstract: The objective of this project is to design and build a high-efficiency neutron detector array consisting of 3000 pixels, with each pixel being 100 microns wide and 4 cm tall, all based on the microstructured semiconductor neutron detector (MSND) technology. The MSND technology resulted in over 40… more

Field-Assembled Component-Based Rotor Blades

Company: Wetzel Engineering, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2013 / 1
Abstract: Wetzel Engineering, Inc., proposes research and development to engineer very large wind turbine rotor blades for land-based machines that avoid expensive and logistically challenging transportation requirements. The proposed solution combines two technologies: Sectional component-based assembly of… more

Fuel-Air Explosive Technologies from Dual-Use Materials

Company: Energetic Materials Research and Enginee Agency/Program/Year/Phase: DOD / SBIR / 2013 / 1
Abstract: ABSTRACT: Energetic Materials Research and Engineering (EMRE), LLC proposes to develop a technique for using residual missile fuel to generate a detonative event that will significantly enhance the blast of the warhead upon impact. This entails the design of an integrated active case and related… more

First Generation of Controlled-Release Bacteriocins/Anti-Microbials

Company: ORBIS BIOSCIENCES, INC. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: Combat ration Intermediate Moisture (IM) products use low pH and water content (aw) to discourage bacterial growth. The long-term goal of this proposal is to maintain the microbial stability of ration components over a two-year shelf life while increasing the pH and aw values for an improved… more

Precision Particle Fabrication-enabled Betamethasone-loaded Microspheres for Tran

Company: ORBIS BIOSCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Current approaches to treat sudden sensorineural hearing loss (SSNHL) do not maintain inner ear drug concentrations within an appropriate therapeutic window for sufficient lengths of time to achieve therapeutic effect.A novel delivery system for long-term,… more