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Scalable, Secure Associative Database

Company: Applied Technical Systems Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: The Associative Model of Data offers a fundamentally different meta-model for data organization than the well-established relational data model. The associative model focuses on Items and Links among items rather than sets of records. We propose to compare and contrast the associative model with two… more

A Variable Pulse Width, Voltage, and Repetition Frequency IGBT-based High Power Radio Frequency Source Driver

Company: Eagle Harbor Technologies, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: The United States Navy is interested in developing small vessel mounted and man-portable directed energy weapons. One key technology in this endeavor is the development of high power radio frequency (HPRF) sources. While much work is being done to advance the state of the art in HPRF sources, the… more

Nanosatellite to Standard Army Handheld Radio Communications System

Company: Tethers Unlimited, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 2
Abstract: TUI proposes to complete the development of two novel technologies that will enable pico-satellites in LEO to efficiently close the link with standard issue handheld radios on the ground. The first technology is a dual-band software-defined radio (SDR) that will provide UHF SATCOM to soldiers on the… more

Forecasting of Solar Eruptions using Statistical Mechanics, Ensemble, and Bayesian Forecasting Methods

Company: NorthWest Research Associates, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: The technological systems on which today's war-fighters depend, reflecting today's society, are vulnerable to the effects of sudden high-energy events from our Sun. Because the propagation speed for sudden increases in X-rays from a solar flare is the speed of light, it is necessary to… more

High Thrust-to-Power Electric Propulsion through Neutral Entrainment

Company: MSNW LLC Agency/Program/Year/Phase: DOD / STTR / 2014 / 2
Abstract: ABSTRACT: State of the art Orbital Transfer Vehicle systems and GEO transfer missions require the demanding combined requirements of both high Thrust-to-Power (greater than 150 mN/kW) and high specific impulse (greater than 3000 s), all at constant power. The 9 kW PROTEAN system is a two-stage… more

High specific power and cost effective solar array for spacecraft, lighter than air vehicles, and UAVs

Company: Soluxra, LLC Agency/Program/Year/Phase: DOD / STTR / 2014 / 1
Abstract: ABSTRACT: The objective of this STTR proposal is to develop and demonstrate a radiation hardened organic-based solar array adaptable to nanosatellites which exhibits flexibility, variable topology, high specific power, and low cost. Organic photovoltaics (OPVs) represent a transformative technology… more

SCALE-UP SYNTHESIS AND OPTIMIZATION OF HIGH-PERFORMANCE ELECTRO-OPTIC POLYMER SYSTEMS FOR ADVANCED PHOTONIC DEVICES

Company: Soluxra, LLC Agency/Program/Year/Phase: DOD / STTR / 2014 / 2
Abstract: ABSTRACT: High-performance organic electro-optic (OEO) polymers can enable the development of advanced EO technologies for achieving significantly reduced energy consumption and bandwidth enhancement in future information and communication technologies. One of the most critical steps in developing… more

Minimal Residual Disease Monitoring by T-cell Receptor Repertoire Profiling

Company: ADAPTIVE TCR CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Minimal Residual Disease Monitoring by T-cell Receptor Repertoire Profiling T-cell neoplasms are generally more aggressive and have poorer outcomes than comparable B-cell lymphomas. In addition, for many of these patients, prognosis following disease relapse is… more

Correlating TCR diversity to immune reconstitution after cord blood transplant

Company: ADAPTIVE TCR CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2013 / 2
Abstract: DESCRIPTION (provided by applicant): Many patients requiring stem cell transplantation for hematological malignancies are unable to find a suitable HLA-matched sibling or unrelated donor. Transplants using stem cells from umbilical cord blood provide an alternative for these patients, allowing… more

SBIR TOPIC 315: DEVELOPMENT OF COMPANION DIAGNOSTICS: ENABLING PRECISION MEDICINE

Company: ADAPTIVE TCR CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: Immunotherapy has emerged as a promising method to treat several cancers. In 2012 the FDA approved a new immunotherapy agent, ipilimumab, for metastatic melanoma. Ipilimumab activates T-cells and globally increases the adaptive immune response and resultsin an enhanced response to the cancer. In a… more

SBIR Phase II: High-yield Fermentation of Sugars to Levulinic Acid

Company: ARZEDA Corp. Agency/Program/Year/Phase: NSF / SBIR / 2013 / 2
Abstract: This Small Business Innovation Research Phase II project focuses on the development of a high-yield fermentation route for the production of levulinic acid (LA). LA is one of the best-suited C5 building blocks for bio-refinery production due to higher value, broad applications, and likely quick… more

STTR Phase I: Synthetic Biology 2.0: A platform for the automated design of cell factories incorporating synthetic enzymes

Company: ARZEDA Corp. Agency/Program/Year/Phase: NSF / STTR / 2013 / 1
Abstract: This Small Business Technology Transfer (STTR) Phase I project brings together computational enzyme design with systems biology to create a fully integrated platform for novel pathway designs. The approach chosen will combine specific databases and a novel pathway synthesis tool. This computational… more

Vaccine Adjuvant for Rapid Tolerance Induction in Allergy Patients

Company: TRIA BIOSCIENCE CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Allergy is a major cause of illness and disability with an estimated 40-50 million people afflicted in the US alone. AIT provides long-term benefits for the patient and its need for optimization creates a compelling business opportunity. There is a very strong… more

An automated, atomic fluorescence-based, field deployable groundwater mercury monitoring system

Company: Brooks Rand Ltd Agency/Program/Year/Phase: DOE / SBIR / 2013 / 2
Abstract: Monitoring mercury contamination in groundwater, surface water, and other natural environments is challenging and expensive, and because samples have to be collected in the field and analyzed in a laboratory, there is a long delay before results are available. The expense of monitoring limits the… more

High-Resolution and Frequency, Printed Miniature Magnetic Probes

Company: Eagle Harbor Technologies, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2013 / 1
Abstract: In modern fusion concepts, inductive pickup loops are one of the primary magnetic diagnostics in tokamaks and small-scale concept exploration experiments. They are used in industries and laboratories that utilize and study low-temperature plasmas. Inductive pickup loops are capable of extremely… more

Development of a Plasma Injector for Supersonic Drag Reduction

Company: Eagle Harbor Technologies, Inc. Agency/Program/Year/Phase: NASA / SBIR / 2013 / 1
Abstract: Methods to reduce the turbulent viscous skin friction stand out as paramount to increasing the energy efficiency, and therefore the aerodynamic efficiency of supersonic aircraft. Eagle Harbor Technology (EHT) proposes to develop and optimize a MHD plasma injector, which will be used to efficiently… more

Advanced Control System for Biofuel Combustion

Company: ENERTECHNIX, INC. Agency/Program/Year/Phase: USDA / SBIR / 2013 / 1
Abstract: Combustion of biomass, especially in small-scale applications, produces high emissions of particulate matter (PM) that have been linked to adverse health effects and global climate change. Current industrial particulate control solutions are prohibitively expensive for use in small scale biomass… more

Novel, Very Wide-Bandwidth Characterization Technique

Company: EOSPACE Inc Agency/Program/Year/Phase: DOD / SBIR / 2013 / 1
Abstract: EOSPACE proposes developing a practical, very-wide-bandwidth electrical characterization technique based on advanced photonic signal processing. The characterization method only requires a high-speed mm-wave source and uses exclusively low-speed optical detection, eliminating the need for high-speed… more

Electromagnetic-Attack-Resistant Electro-Optic LiNbO3 Modulator

Company: EOSPACE Inc Agency/Program/Year/Phase: DOD / SBIR / 2013 / 1
Abstract: The objective is to develop a wideband, high-sensitivity, high RF power handling optical modulator suitable for use in low-noise microwave photonic links associated with military and commercial antenna applications. Specifically, the modulator will be designed to be highly-resistive to… more

Autologous HIV-1 resistant T cells through accelerated CCR5 gene disruption

Company: PRECISION GENOME ENGINEERING, INC. Agency/Program/Year/Phase: HHS / STTR / 2013 / 2
Abstract: DESCRIPTION (provided by applicant): Treating patients infected with Human Immunodeficiency Virus-1 (HIV-1) is a substantial clinical challenge with evolving pharmaceutical drug and dosing options. Treatments should improve the health and quality of life for HIV-infected individuals by reducing… more

Low-Energy Rotary Shear for Sub-millimeter Particle Production

Company: FOREST CONCEPTS, LLC Agency/Program/Year/Phase: DOE / SBIR / 2013 / 1
Abstract: Inexpensive biofuels are essential to the national economic and environmental stability of the United States. Pathways are well established to ferment sugars derived from biomass into fuels and bioproducts. However, there is a massive gap between the physical form of raw cellulosic biomass and the… more

Low Energy Comminution of Herbaceous Biomass Feedstocks

Company: FOREST CONCEPTS, LLC Agency/Program/Year/Phase: USDA / SBIR / 2013 / 1
Abstract: Size reduction, or comminution, is a fundamental processing step for lignocellulosic biomass feedstocks used as a raw material for conversion to biofuels. Grinding or milling of herbaceous materials such as corn stover, switchgrass, miscanthus and other biofuel feedstocks consumes a lot of energy,… more

Programmable Picosat Transceiver

Company: Tethers Unlimited, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2013 / 2
Abstract: ABSTRACT: The goal of the Space Test Program is to enable the US Air Force to rapidly develop emerging space technologies by providing economical flight opportunities to increase a technology"s TRL. Over the past decade, the CubeSat form factor has emerged as an economical platform for testing… more

SWIFT-HPX - High Data Rate Ka-band Commications for Small Satellites

Company: Tethers Unlimited, Inc. Agency/Program/Year/Phase: NASA / SBIR / 2013 / 1
Abstract: Leveraging TUI's SWIFT software defined radio (SDR) architecture, we propose to develop a 100 Mbps downlink and intersatellite crosslink capability with ranging and timing synchronization capabilities to enable more sophisticated CubeSat and small satellite missions. This effort will focus on… more

SWIFT-nanoLV Avionics Platform

Company: Tethers Unlimited, Inc. Agency/Program/Year/Phase: NASA / SBIR / 2013 / 1
Abstract: With the increased demand for and utility of nano- and micro-satellites, the demand for responsive, low-cost access to space has also increased. To meet this demand, multiple private companies are pursuing the development of nano- and micro-launch vehicles (NMLV). However, NMLV builders lack… more