SHARE Under Uncertainty
Company: 21st Century Systems, Incorporated Agency/Program/Year/Phase: DOD / STTR / 2012 / 1Abstract: In the GMD battlespace, it"s critical to rapidly ascertain specific identifying characteristics of a track so follow-on sensors can match the same track. Currently, sensors communicate track data with differing biases and uncertainties with little data-rich content and attempts to utilize track… more
Fusion with Uncertainty Reasoning using Nested Assessment Characterizer Elements (FURNACE)
Company: 21st Century Systems, Incorporated Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1Abstract: Situation/threat modeling and threat prediction require higher levels of data fusion to provide actionable information to the warfighter. Beyond sensor data and sources the analyst has control over, the use of out-sourced and re-sourced data are becoming more common. However, the current data fusion… more
Self-Regulating Anomaly Detector (SeRADe)
Company: 21st Century Systems, Incorporated Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1Abstract: Today"s intelligence exploitation has an information challengethere is a great deal of data being processed by a large number of analysts with insufficient ability to identify anomalies in the data. The process needs a capability that can facilitate a rapid understanding of complex information… more
Agent-Enabled Logistics Enterprise Intelligence System (AELEIS)
Company: 21st Century Systems, Incorporated Agency/Program/Year/Phase: DOD / SBIR / 2012 / 2Abstract: Army logisticians and fleet managers need an effective method to extract actionable information from their large data stores. They need to extract root cause and case-based analysis to diagnose or predict breakdowns. An Enterprise Intelligence System that extracts data from multiple sources, fuses… more
Development of Ultrafine Particles for Intranasal Delivery of Antipsychotics
Company: LNKCHEMSOLUTIONS Agency/Program/Year/Phase: HHS / STTR / 2012 / 1Abstract: DESCRIPTION: The goal of the proposed project is to develop a biocompatible ultrafine particle-based vector system for the intranasal delivery of clozapine for the pharmacological therapy of treatment- resistant schizophrenic disorders and their associatedsuicidal behavior. The rationale behind the… more
Early Detection of Pancreatic Cancer Using Ice COLD-PCR
Company: Transgenomic, Inc. Agency/Program/Year/Phase: HHS / STTR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): Ninety percent of all pancreatic cancers are pancreatic ductal adenocarcinoma (PDAC). PDAC diagnosis is difficult, usually occurring in the late stages of disease. Patients with these advanced tumors typically respondpoorly to therapy. Post diagnosis, median… more
Ex Vivo Tolerance for Xenotransplantation of Diabetes P2
Company: XIMEREX, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2Abstract: DESCRIPTION (provided by applicant): Type I diabetes is a widespread disease in which insulin producing pancreatic islets are lost, leading to unstable glucose levels. If the islets can be replaced, as with transplantation, then diabetes can be reversed.Human islets have limited utility because of… more
Lightweight RSG Launcher Components and AURE Composite Cansiters
Company: Pacific Engineering, Inc Agency/Program/Year/Phase: DOD / SBIR / 2012 / 2Abstract: NAVSEA Undersea Defensive Warfare Systems Program office is developing a Surface Ship Torpedo Defense program that utilizes Anti-Torpedo-Torpedo (ATT) hard kill capability for high value unit (HVU) platforms (Carriers and Combat Logistics Force (CLF) ships). The CAT, a hard kill countermeasure,… more
Lightweight RSG Launcher Components and AURE Composite Cansiters
Company: Pacific Engineering, Inc Agency/Program/Year/Phase: DOD / SBIR / 2012 / 2Abstract: NAVSEA Undersea Defensive Warfare Systems Program office is developing a Surface Ship Torpedo Defense program that utilizes Anti-Torpedo-Torpedo (ATT) hard kill capability for high value unit (HVU) platforms (Carriers and Combat Logistics Force (CLF) ships). The CAT, a hard kill countermeasure,… more
RADIOGRAPHIC CONTRAST TO DIFFERENTIATE CAVITATED FROM NON-CAVITATED DENTAL CARIES
Company: FIREFLY HEALTH INNOVATIONS NE, INC. Agency/Program/Year/Phase: HHS / STTR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): This project relates directly to the PHS 2011-2, Omnibus Solicitation for SBIR/STTR Grant Application page NIDCR 110: Development of instrumentation for early caries detection and comparison studies on specificity andselectivity with respect to current clinical… more
SBIR Phase I: PET Radiotracer Synthesis
Company: Ground Fluor Pharmaceuticals, Inc. Agency/Program/Year/Phase: NSF / SBIR / 2012 / 1Abstract: This Small Business Innovation Research Phase I project will support a new synthetic chemical approach for the creation of positron emission tomography (PET) imaging products to manage neurodegenerative disorders, cancer, and cardiovascular disease. Creating these imaging products relies on the… more
AMADEUS
Company: 21st Century Systems, Incorporated Agency/Program/Year/Phase: DOD / SBIR / 2011 / 1Abstract: ABSTRACT: Airspace congestion with RPAs in close proximity to manned systems poses a serious threat for mishap. At present, RPA pilot training in airspace management is minimal. RPA operator training should consider communications, asset management, deconfliction, and coordination among RPA and… more
Augur
Company: 21st Century Systems, Incorporated Agency/Program/Year/Phase: DOD / SBIR / 2011 / 1Abstract: History is replete with"intelligence failures"that were not intelligence weaknesses at all, but an inability to"put the pieces together"in time. Quintessentially, the 9/11 attack is an example, but it is merely the one most remembered. Pieces of intelligence were collected, like… more
Modular Video Interface for Intelligence, Surveillance, and Reconnaissance (M-VIISR)
Company: 21st Century Systems, Incorporated Agency/Program/Year/Phase: DOD / SBIR / 2011 / 1Abstract: Intelligence, Surveillance, and Reconnissance (ISR) systems are diverse, and each one comes with its own interface to process and present imagery to the warfighter. When coupled with the complexities of processing multiple types of unmanned aerial vehicle (UAV) full motion video, it creates an… more
Measure and Alert on Data Omitted by Compression (MADOC)
Company: 21st Century Systems, Incorporated Agency/Program/Year/Phase: DOD / SBIR / 2011 / 1Abstract: Critical information can be lost when lossy compression techniques are used in bandwidth limited environments, such as from unmanned systems. More serious, this lost information is unknown to the analyst, which can lead to incorrect analysis and potentially fatal conclusions. 21st Century Systems,… more
Smart Multimodal Image Registration and Fusion (SMIRF)
Company: 21st Century Systems, Incorporated Agency/Program/Year/Phase: DOD / SBIR / 2011 / 2Abstract: To improve safety, modern submarine surface imaging systems have multiple camera modes, such as optical, infrared, and more. Current systems display modalities independently, compelling the submariner to switch between sensors manually to glean the relevant information. Following a successful Phase… more
SBIR Phase II: Sample Classification and Biomarker Discovery by Comprehensive Metabolomic Analysis
Company: GC Imaging Agency/Program/Year/Phase: NSF / SBIR / 2011 / 2Abstract: This Small Business Innovation Research Phase II project proposes to develop a system for automated classification of biological samples and discovery of biomarkers. The system will be designed to perform comprehensive pattern analysis of state-of-the-art biochemical separations generated by… more
Nanoparticles and Nanocapsules for Glioma Targeting
Company: LNKCHEMSOLUTIONS Agency/Program/Year/Phase: HHS / SBIR / 2011 / 2Abstract: DESCRIPTION (provided by applicant): Malignant gliomas represent a heterogeneous family of tumors that are poorly responsive to current treatments. A major obstacle to the effective management of these lesions involves the difficulty in delivering adequateconcentrations of therapeutics to the tumor… more
eukaryotic expression vectors resistant to transgene silencing
Company: NATURE TECHNOLOGY CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2011 / 2Abstract: DESCRIPTION (provided by applicant): Plasmid-directed gene expression is now near the efficacy barrier that to date has prevented commercialization of plasmid-based therapies for human health applications. Previous innovations such as electroporation (EP)increased transgene expression through more… more
Response-Selective C5a Agonist for the Treatment of Asthma
Company: PROMMUNE LLC Agency/Program/Year/Phase: HHS / STTR / 2011 / 1Abstract: DESCRIPTION (provided by applicant): An unmet need in the treatment of allergic asthma is an effective therapeutic strategy that focuses on an underlying cause of the disease rather than merely treating or managing its symptoms. At least one well- accepted underlying contributor to the… more
SBIR Phase I: Mobile Green - Mobile Health Card
Company: Mobile Green Agency/Program/Year/Phase: NSF / SBIR / 2011 / 1Abstract: This Small Business Innovation Research Phase I project will attempt to resolve inefficiencies in the processing of health insurance claims. A total of 8.3-18.1 billion transactions, including eligibility verification, claim submission, etc., are performed annually in healthcare with only 30-50% of… more
Hazardous Material Satellite Storage Lockers
Company: Pacific Engineering, Inc Agency/Program/Year/Phase: DOD / SBIR / 2011 / 1Abstract: Navy ships require the use of hazardous materials (HM) such as hydraulic fluid, paint, acids, corrosives, etc. for daily operations. Navy safety regulations and HM management procedure (i.e. OPNAVINST 5100.19E and CHRMIP), require designated HM storerooms for bulk storage of flammable and corrosive… more
SCADA Hawk - An Integrated Anti-Tamper Technology
Company: Technical Support Inc. Agency/Program/Year/Phase: DOD / STTR / 2010 / 1Abstract: Our proposal is to develop SCADA Hawk: an integrated anti-tamper technology that uses a hardware-software combined methodology for the observational monitoring of existing systems with selective reaction capabilities. By enabling detailed monitoring capabilities our goal is to isolate anomalies in… more
SBIR Phase I: Commercialization of the CEENBoT Educational Platform for K-16
Company: CEENBoT Agency/Program/Year/Phase: NSF / SBIR / 2010 / 1Abstract: This Small Business Innovation Research (SBIR) Phase I research project focuses on the demonstrating the technical feasibility and a commercialization path for a well-established educational robotics platform. This innovative Computer and Electronics Engineering Robot (CEENBoT), is a hands-on tool… more
An Enhanced Performance Training and Support System for Individuals with Autism Spectrum Disorders
Company: The Prevention Group, LLC Agency/Program/Year/Phase: ED / SBIR / 2010 / 1Abstract: This project develops and evaluates the Enhanced Performance Training and Support System (EPTSS) to train and support individuals with autism spectrum disorder (ASD) in: behavioral training, modeling, self-management, and visual cues using available technology such as the iPod Touch/iPad. Phase I… more