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Development of Technologies that Address the Complex Architecture of the Face During the Treatment of Severe Facial Burn Injury

Company: KeraNetics, LLC Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: With the advent of improved body armor and vehicles and the enemy"s use of the improved explosion device (IED) in the most recent conflicts, blast injuries and related burns to the face have become more and more common among our Wounded Warriors. Pathological scarring, which often results in… more

Post-IED Hull Inspection Tool

Company: Corvid Technologies, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 2
Abstract: On today"s battlefields, vehicles are at risk of encountering improvised explosive devices (IEDs). Fortunately, not all of these result in complete vehicle loss. Following events at both ends of the severity spectrum, Battle Damage Assessment and Repair (BDAR) and event reconstruction efforts… more

Prime Power System Development for Active Denial Technology (ADT) and High-Power Radio-Frequency (RF) Systems

Company: Higher Power Engineering Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: Higher Power Engineering proposes to develop a compact and lightweight prime power plant operating from JP-8 fuel. Capacity of 155kW continuos, which exceeds the Navy duty-cycle requirements. Unit exceeds all specifications of size, weight, and fuel efficiency. The proposed unit is projected at… more

Hybrid Veil Material for ESD/EMI Applications

Company: NanoTechLabs Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 2
Abstract: The objective of this proposal is to develop a hybrid conductive veil technology for use in UCASS or FA/xx and also as a replacement or repair of the existing conductive metallic ground planes on legacy platforms. The hybrid veil system can be made into a prepreg and bonded directly to the composite… more

Integrated GaN T/R MMIC for AESA Radar

Company: Vadum Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: Vadum proposes to develop an innovative, highly integrated, power-conserving GaN T/R MMIC for radar applications. We will leverage expertise in high efficiency, high power Gallium Nitride Power Amplifiers, low loss GaN RF switches, Low Noise Amplifiers, GaN Monolithic Microwave Integrated Circuits,… more

Signals of Opportunity as a Covert Alternative Fix Source for Submarines While Submerged

Company: Physical Devices Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: We propose a Phase I analysis of Signals of Opportunity (SOO), including Magnetic Velocity and Position (MVP) sensing, breakthrough passive geo-referenced navigation technology. MVP leverages classical electromagnetics to determine velocity and position with GPS-level accuracy at any depth or… more

Nondestructive Concrete Characterization System

Company: NLA Diagnostics LLP Agency/Program/Year/Phase: DOD / STTR / 2014 / 2
Abstract: During covert operations, the U.S. Army may be required to breach a concrete structure using a controlled explosion. When choosing the most effective charge size and placement, it is vital to perform a rapid field assessment of the material and structural properties of the target structure. However,… more

Develop a Methodology for Cyber-Electronic Warfare Battle Damage Assessment (BDA) using Game Theory

Company: Vigilant Systems Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: The Cyber Battle Damage Assessment Tool (CyBDAT) will allow warfighters to quantify the probabilities associated with CNA, CNE and EA and facilitate for the direct comparison of cyber attacks to kinetic attacks in mission planning. CyBDAT creates a directed graph Markov attack model of the cyber… more

Deep Analytics for Data in Cyber-Physical Systems

Company: Vigilant Systems Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: Visual Analytics Managers (VAMs) for Cyber-Physical Systems (CPS) will allow users to gain insight into the CPS with state-of-the-art analytics and artificial intelligence and provide human-in-the-loop interaction with the CPS. Our VAM toolkit builds around a Scala Akka actor framework, allowing… more

KeraStat(TM) Burn Gel and Halofuginone to Prevent Scar Contracture after Burn Injuries

Company: KeraNetics, LLC Agency/Program/Year/Phase: DOD / SBIR / 2013 / 1
Abstract: This Phase I project is relevant to the ultimate goals of this program announcement given the prevalence of the IED which often creates complex burn wounds on the face and skin that often form hypertrophic scars that often contract over time. Burn wound healing is a complex process that includes… more

Flowable keratin biomaterials for improving infection control and wound healing, Phase 2.

Company: KeraNetics, LLC Agency/Program/Year/Phase: DOD / SBIR / 2013 / 2
Abstract: Improvements in body armor, availability of equipment, and decreased patient transport times have dramatically improved Soldiers"survival of combat injuries. Data suggests that future conflicts will require more aggressive wound management at the point of injury to deal with more complex… more

Novel Manufacturing Processes for Tissue Engineered Vascular Grafts

Company: HUMACYTE, INC. Agency/Program/Year/Phase: HHS / SBIR / 2013 / 2
Abstract: DESCRIPTION (provided by applicant): This Phase IIB SBIR application is responsive to NHLBI RFA HL-13-016, NHLBI SBIR Phase IIB Bridge Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood and Sleep Disorders and Diseases (R44) . This RFA solicits work on basic,… more

SBIR Phase II Topic 272: Low-Cost Microfluidic System for Detection of CTCs; Peri

Company: BIOFLUIDICA MICROTECHNOLOGIES, LLC Agency/Program/Year/Phase: HHS / SBIR / 2013 / 2
Abstract: Not Available

Dynamic Narrative Generation Software To Improve Social And Behavioral School Readiness Skills Needed For The Successful Transition To Grade School

Company: 3-C Institute for Social Development Agency/Program/Year/Phase: ED / SBIR / 2013 / 1
Abstract: The project team is developing a prototype of a web-based intervention for pre-kindergarten and kindergarten students to prepare for the transition to grade school. The product will support students as they create stories using a step-by-step scripted interactive process. The stories will focus on… more

Hall Of Heroes: An Interactive Social Tutoring System To Improve And Measure Social Goals For Students In Preparation For Transition To Middle School

Company: 3-C Institute for Social Development Agency/Program/Year/Phase: ED / SBIR / 2013 / 2
Abstract: Hall of Heroes will be a web-based game for fifth graders to engage with pedagogical agents (animated life-like characters) to solve tailored social problem solving tasks and build social skills to use in challenging situations. Instructional content will focus on six core Social Skill Units… more

Dynamic E-Learning to Improve Postsecondary Transition Outcomes for Secondary Students with High Functioning Autism

Company: 3-C Institute for Social Development Agency/Program/Year/Phase: ED / SBIR / 2013 / 1
Abstract: This project team will develop a web-based product to engage 11th and 12th grade high school students with HF-ASD in a self-paced online interactive course to learn about the transition to college, learn specific resilience strategies for coping with the transition to college, and to practice… more

Accommodation integrated technology to minimize the impact of disability on students’ assessment performance

Company: 3-C Institute for Social Development Agency/Program/Year/Phase: ED / SBIR / 2013 / 1
Abstract: There is growing interest in computerized systems to increase accessibility of assessments for students with disabilities. Technology offers an ideal platform for implementing Universal Design (UD) principles for assessment to better accommodate student diversity and support broad student… more

Web-based Tool for the Dissemination of Evidence-Based Interventions for ATOD Pre

Company: 3-C INSTITUTE FOR SOCIAL DEVELOPMENT Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Over the past several decades, a large number of evidence-based prevention initiatives for alcohol, tobacco, and other drug (ATOD) use have been rigorously tested and shown to be efficacious. However, despite availability, evidence-based interventions (EBIs) for… more

Neurorestorative Strategy for Diabetic Peripheral Neuropathy

Company: 3-C INSTITUTE FOR SOCIAL DEVELOPMENT Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Early childhood research indicates that school readiness is a key determinant of a successful transition to school. Between 9.5% and 14.2% of young children experience social-emotional problems that negatively impact school-readiness, and nearly half of children… more

Droplet-Based Automation of Complex Workflows for Synthetic Biology

Company: ADVANCED LIQUID LOGIC Agency/Program/Year/Phase: DOD / STTR / 2013 / 1
Abstract: Large-scale genome engineering represents a broad group of technologies, all of which stand to impact the manufacturing of a range of biological and chemical products. While the power of these methods to increase the production of biologically-driven manufacturing processes has been previously… more

Automated Sample Preparation for Next Generation Sequencing Cancer Diagnostics

Company: ADVANCED LIQUID LOGIC Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): As more diverse genetic links are established with cancer, the utility of one-gene-one-test diagnostics is diminished. In addition, biopsies are mixed populations of tumor and normal tissue, requiring deconvolution oftumor and non-tumor genoptypes to accurately… more

Distributed REMD Simulation for Probing Alzheimer Molecular Mechanisms

Company: ADVANCED LIQUID LOGIC Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION: Mass spectrometry is a multiplex technology for high-throughput analysis of biomolecules in newborn screening and clinical laboratories. Complexity in sample preparation has been recognized as the main bottleneck in well-established MS methods. Digital microfluidics is a rapidly… more

Point-of-Care Nucleic Acid Test for Cytomegalovirus for Newborn Hearing Screening

Company: ADVANCED LIQUID LOGIC Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Universal newborn hearing screening is mandated in the US and is performed in the postpartum hospital setting. Current physiology-based hearing screening tests are unable to detect late-onset hearing loss caused by cytomegalovirus (CMV) infection. Therefore, a… more

Point-of-Care Nucleic Acid Test for Cytomegalovirus for Newborn Hearing Screening

Company: ADVANCED LIQUID LOGIC Agency/Program/Year/Phase: HHS / SBIR / 2013 / 2
Abstract: DESCRIPTION (provided by applicant): Universal newborn hearing screening is mandated in the US and is performed in the postpartum hospital setting. Current physiology-based hearing screening tests are unable to detect late-onset hearing loss caused by cytomegalovirus (CMV) infection. Therefore, a… more

Targeting mutant KRAS for cancer therapy

Company: ALDERON BIOSCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION: Lead toxicity is a serious but preventable public health problem in the U.S. and elsewhere in the world. Even at very low levels, ingested lead causes irreversible damage, especially in young children, resulting in decreased IQ, learning disabilities, attention deficit disorders,… more