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Anti-Exploitation Software Protection Systems

Company: Siege Technologies, LLC Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: State-of-the-art software protection and anti-tamper systems move critical software and data"out-of-band"to the adversary, by using a hypervisor or on"secure"hardware. Unfortunately, the systems running this software are built using untrusted commercial-off-the-shelf (COTS) parts… more

Cyano-Map: Linking cyanobacteria metrics and human health

Company: Applied Geosolutions, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Research at the intersection of limnology and public health is showing that toxins produced from cyanobacteria act as an environmental trigger for Amyotrophic Lateral Sclerosis (ALS) commonly known as Lou Gehrig's Disease. Additional linkages are being made… more

High Friction, Conforming Boat Capture and Transfer System

Company: C3I, INC. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: The boat transfer, launch, and recovery system proposed will utilize a system of composite moving ways, cradle, and configurable bouyant bladders, controlled by the Advanced Communication and Control System (ACCS) to safely launch, recover, and transfer a variety of boats ranging in size as a… more

An Unobtrusive, Multi-individual Gait Monitor

Company: RESPONSE APPLICATIONS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): We will develop an instrument to improve the healthcare of the most frail members of the elderly community. This population; elderly or recovering patients living at home or in an extended care facility is too frail toleave this environment and, as such, is… more

Research Platform Integrating Patient Reported and Clinical Outcomes Data Sources

Company: DYNAMIC CLINICAL SYSTEMS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): While large, prospective, blinded trials are the gold standard in clinical research, they require significant commitments of resources and time. Further, since these trials seek the answer to rather specific questions,the applicability and scalability of data… more

Optimized Thermal Battery for Weight- and Size-Constrained Applications

Company: Erigo Technologies, LLC Agency/Program/Year/Phase: DOD / SBIR / 2012 / 2
Abstract: Thermal batteries are a power source for most MDA weapons systems. Some of these applications place severe constraints on battery weight and size. The key components of thermal batteries are typically made by hydraulically pressing powders into"pellets". The pellets must be greater than… more

Ultrahigh Temperature Materials for Missile Defense Propulsion and Aerothermal Applications

Company: Exothermics, Inc. Agency/Program/Year/Phase: DOD / STTR / 2012 / 2
Abstract: The notional performance parameters and kinematic requirements for the SM3 Blk IIB mission would benefit from the availability of advanced materials manufacturing methods that could enhance the technical properties and lower the cost of TDACS components. This Phase 2 STTR proposal addresses the… more

Depletion of Dendritic Cells by Immunotoxin as Therapy for Myocardial Infarction

Company: CELDARA MEDICAL, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: DESCRIPTION (provided by applicant): MI is the leading cause of death in the developed world, including the United States. In 2005 over 8.1 million Americans had an MI; 30% died before reaching hospital and 10% died after hospitalization. It is the 70% whoreach hospital that we believe we can help -… more

ChNKG2D-Targeted Cellular Cancer Therapy: Phase I Clinical Trial

Company: CELDARA MEDICAL, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: DESCRIPTION (provided by applicant): The global burden of cancer doubled between 1975 and 2000. Cancer became the leading cause of death worldwide in 2010, and is projected to double again by 2020 and to triple by 2030. This horrible disease has touched each of us, and despite enormous investments… more

Preclinical Development of a Novel Plaque-Regressing Therapy For Atherosclerosis

Company: CELDARA MEDICAL, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Cardiovascular disease (CVD) is the leading cause of death in the world. The staggering mortality rate is expected to increase significantly in the next ten years. In the U.S., an estimated 81 million adults will haveone or more types of cardiovascular disease… more

Safe and effective anti CD154 antibodies for therapeutic intervention

Company: IMMURX LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): In both animal proof of concept studies and preliminary clinical trials, there is ample data demonstrating the potential therapeutic benefits o CD154 blockade for treatment of autoimmune diseases and organ transplantation. However, development of ?CD154 as a… more

Lightweight Electromagnetic Interference (EMI) Shielding System for Aircraft Avionics

Company: Nanocomp Technologies Inc. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: A key technology enabler for next generation EMI shielding applications is low loss, lightweight, flexible, conductive carbon nanotube (CNT) tape. The primary goal of this effort is to determine the optimal geometry for a CNT based EMI shield to provide equivalent shielding effectiveness of cable… more

High-Vacuum Package for MEMS Inertial Sensors

Company: Creare Inc. Agency/Program/Year/Phase: DOD / STTR / 2012 / 1
Abstract: High-sensitivity resonant vibratory microelectromechanical systems (MEMS) sensors are typically vacuum packaged in discreet packages. Wafer-scale vacuum packaging offers size, weight, and cost advantages, and the packages are more shock and vibration tolerant. However, the high internal pressures… more

Low-Cost UUV Deployed Self-Scuttling Acoustic Source for Littoral Bottom Surveys

Company: Creare Inc. Agency/Program/Year/Phase: DOD / STTR / 2012 / 1
Abstract: Ocean bottom acoustic surveys are an important component of a number of littoral missions. Knowledge of local ocean bottom acoustic properties is necessary for modern anti-submarine warfare (ASW) and mine and other buried object detection missions to be successful. Bottom-hugging Unmanned Undersea… more

Diver Hearing Protection System

Company: Creare Inc. Agency/Program/Year/Phase: DOD / STTR / 2012 / 1
Abstract: Although helmeted divers are routinely exposed to noise levels that pose an increased risk of hearing damage, modern dive helmets do not include additional hearing protection. Noise sources from underwater tools, breathing noise, and high-volume communications all contribute to a dangerous noise… more

An Ultra Low Power Cryo-Refrigerator for Space

Company: Creare Inc. Agency/Program/Year/Phase: NASA / SBIR / 2012 / 2
Abstract: Future NASA Space Science Missions will incorporate detectors, sensors, shields, and telescopes that must be cooled to cryogenic temperatures. An enabling technology for these missions is advanced cryocoolers that can provide continuous and distributed cooling with minimal input power. On this… more

An Advanced Wet Expansion Turbine for Hydrogen Liquefaction

Company: Creare Inc. Agency/Program/Year/Phase: NASA / SBIR / 2012 / 2
Abstract: This proposal is responsive to NASA SBIR Topic X10.01, specifically, the need for efficient small- to medium-scale hydrogen liquefaction technologies, including domestically produced wet cryogenic turboexpanders. Future NASA missions will require hydrogen liquefaction systems for spaceport,… more

A Turbo-Brayton Cryocooler for Aircraft Superconducting Systems

Company: Creare Inc. Agency/Program/Year/Phase: NASA / SBIR / 2012 / 1
Abstract: Hybrid turbo-electric aircraft with gas turbines driving electric generators connected to electric propulsion motors have the potential to transform the aircraft design space by decoupling power generation from propulsion. Resulting aircraft designs such as blended-wing bodies with distributed… more

Water Recovery for Regenerative Life Support Systems

Company: Creare Inc. Agency/Program/Year/Phase: NASA / SBIR / 2012 / 1
Abstract: Thermal and environmental control systems for future exploration spacecraft must meet challenging requirements for efficient operation and conservation of resources. Regenerative CO2 removal systems are attractive for these missions because they do not use consumable CO2 absorbers. However, these… more

A Multi-Environment Thermal Control System With Freeze-Tolerant Radiator

Company: Creare Inc. Agency/Program/Year/Phase: NASA / SBIR / 2012 / 1
Abstract: Future space exploration missions require advanced thermal control systems (TCS) to dissipate heat from spacecraft, rovers, or habitats to external environments. We propose to develop a lightweight, reliable TCS to effectively maintain cabin and equipment temperatures under widely varying heat… more

Miniature Gas Chromatograph Mass Spectrometer for In-Situ Resource Utilization

Company: Creare Inc. Agency/Program/Year/Phase: NASA / SBIR / 2012 / 1
Abstract: In situ resource utilization (ISRU) is essential for several of NASA's future flagship missions. Currently envisioned ISRU plants include production of oxygen from hydrogen reduction of lunar regolith and extraction of water from Martian regolith or asteroid material. These ISRU processes… more

Non-Contact Inspection System

Company: Creare Inc. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: ABSTRACT: Inspection of machined composite laminate parts is currently performed using a precision milling machine (PMM) to maneuver a touch probe. When performed on complex parts, this inspection process is extremely time consuming and ties up the PMM for longer time periods than the actual… more

Low-Cost Hybrid Cryocoolers for Next-Generation Focal Plane Arrays

Company: Creare Inc. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: ABSTRACT: Future airborne imaging sensors will utilize next-generation focal plane technology that must operate at temperatures from 25 to 30 K. Passive cooling techniques such as stored cryogens are heavy and logistically undesirable. Current airborne cryocoolers are too inefficient in this… more

A CubeSat-Compatible Neutral Wind Sensor

Company: Creare Inc. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: ABSTRACT: CubeSats provide a new, low-cost platform for space weather missions. They enable new mission paradigms, such as the ability to perform multiple measurements of the same physical phenomena globally from several satellites, in contrast to high accuracy measurements of multiple phenomena… more

Improved Mass Balancing of Turbo Machine Rotors

Company: Creare Inc. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: ABSTRACT: The efficient, effective balancing of jet engine rotors and subassemblies continues to be a challenge for key aerospace applications. While manufacturing methods for balancing have improved significantly over the last ten years, measurement methods and procedures and fixturing have not… more