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Dipstick Assay for Field Detection of Leishmania Parasites using Quantum Dots

Award Information

Agency:
Department of Defense
Branch:
Office of the Secretary of Defense
Award ID:
76507
Program Year/Program:
2005 / SBIR
Agency Tracking Number:
O043-H08-3058
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Agave BioSystems, Inc.
P.O. Box 100 Ithaca, NY 14850-
View profile »
Woman-Owned: No
Minority-Owned: Yes
HUBZone-Owned: Yes
 
Phase 1
Fiscal Year: 2005
Title: Dipstick Assay for Field Detection of Leishmania Parasites using Quantum Dots
Agency / Branch: DOD / OSD
Contract: W81XWH-05-C-0094
Award Amount: $100,000.00
 

Abstract:

A PCR based assay has been developed to detect Leishmania parasites, but PCR requires sophisticated laboratory instruments and trained personnel to interpret the data. The parasite can also be identified in infected sand flies by skillful dissection and microscopic examination but this is subjective and not appropriate for field testing. Antibodies are available that can detect Leishmania parasites and a standard ELISA could be used for detection, but this like the other assays requires trained personnel and sophisticated laboratory instruments. To overcome these shortcomings, Agave BioSystems proposes to develop a dipstick assay to provide a practical tool for assessment of Leishmania infected sand flies in the field. Our novel dipstick assay would use new fluorescent quantum dot technology for detection. This quantum dot assay would be considerably more specific, sensitive, and stable making it superior to standard colorimetric dipstick assays.

Principal Investigator:

Theresa Curtis
Staff Scientist
6072720002
tcurtis@agavebio.com

Business Contact:

Noe Salazar
President
5126711369
nsalazar@agavebio.com
Small Business Information at Submission:

AGAVE BIOSYSTEMS, INC.
P.O. Box 80010 Austin, TX 78708

EIN/Tax ID: 161551819
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No