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In-line, Real-time monitoring of Arsenic in Drinking Water

Award Information

Agency:
Department of Defense
Branch:
Air Force
Award ID:
67891
Program Year/Program:
2004 / SBIR
Agency Tracking Number:
F041-302-1202
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Agave BioSystems, Inc.
P.O. Box 100 Ithaca, NY -
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2004
Title: In-line, Real-time monitoring of Arsenic in Drinking Water
Agency / Branch: DOD / USAF
Contract: FA9300-04-M-1001
Award Amount: $100,000.00
 

Abstract:

In this Phase I, Agave BioSystems proposes a novel approach for the development of a rapid and sensitive detection system for arsenic in drinking water based on the bioluminescent protein aequorin. The simplicity and ruggedness of this technology has the potential for providing low cost, on-line, real-time monitoring for arsenic as part of a treatment plant process control system. Aequorin is a unique calcium-sensitive photoprotein originally isolated from the jellyfish Aequorea aequorea. In nature, when aequorin is in the presence of calcium, it triggers the chemical reaction that results in the production of light. Agave BioSystems proposes to engineer a genetically modified aequorin that is capable of generating light in the presence of arsenic by replacing the aequorin calcium binding sites with arsenic binding sites. This will result in a specific and rapid arsenic detection mechanism. Subsequently, the engineered molecule will be integrated into a self-contained biosensor for the rapid, and sensitive detection of arsenic in drinking water.

Principal Investigator:

Mehran Pazirandeh
Staff Scientist
6072720002
mehranp@agavebio.com

Business Contact:

Noe Salazar
President
5126711369
nsalazar@agavebio.com
Small Business Information at Submission:

AGAVE BIOSYSTEMS, INC.
P.O. Box 80010 Austin, TX 78708

EIN/Tax ID: 161551819
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No