USA flag logo/image

An Official Website of the United States Government

Biological Degradation of Chemical Agents

Award Information

Agency:
Department of Defense
Branch:
Defense Advanced Research Projects Agency
Award ID:
63534
Program Year/Program:
2003 / SBIR
Agency Tracking Number:
03SB2-0470
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Agave BioSystems, Inc.
P.O. Box 100 Ithaca, NY 14850-
View profile »
Woman-Owned: No
Minority-Owned: Yes
HUBZone-Owned: Yes
 
Phase 1
Fiscal Year: 2003
Title: Biological Degradation of Chemical Agents
Agency / Branch: DOD / DARPA
Contract: W31P4Q04CR065
Award Amount: $99,000.00
 

Abstract:

Current methods used for the destruction of CW agents are cumbersome, require extensive capital equipment such as incinerators and water reactors and pose potential environmental problems themselves. A novel approach for the destruction of CW agentsinvolves genetically engineering microorganisms to produce recombinant enzymes that can efficiently degrade CW agents. Such a system would allow these toxic compounds to be efficiently degraded to harmless products. There are a number of advantages to abiological based system for degrading CW agents. First, a properly designed biological system would be easy to use by non-science personnel, such as Special Operation units of the armed forces. Also, a biological-based system would be cost effectivebecause it would be self-generating, and due to their catalytic nature, each enzyme molecule can degrade many molecules of a CW agent. Agave BioSystems proposes to develop a biologically based system for the efficient and safe destruction of CW agents,particularly the non-volatile persistent substances such as VX. This effort involves the development of a genetically engineered microbial system based on the efficient CW degrading enzyme organophosphate hydrolase (OPH).

Principal Investigator:

Mehran Pazirandeh
Staff Scientist
6072720002
mehranp@agavebio.com

Business Contact:

Noe Salazar
President
5126711369
nsalazar@agavebio.com
Small Business Information at Submission:

AGAVE BIOSYSTEMS, INC.
P.O. Box 80010 Austin, TX 78708

EIN/Tax ID: 161551819
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No