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Miniature Flow Cytometer and Cell Sorter for Use in Low Gravity

Award Information

Agency:
National Aeronautics and Space Administration
Branch:
N/A
Award ID:
52209
Program Year/Program:
2001 / SBIR
Agency Tracking Number:
NASA1070
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Agave BioSystems, Inc.
P.O. Box 100 Ithaca, NY -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2001
Title: Miniature Flow Cytometer and Cell Sorter for Use in Low Gravity
Agency: NASA
Contract: N/A
Award Amount: $70,000.00
 

Abstract:

Conventional fluorescence-activated cell sorters (FACSs) are widely used to study eukaryotic cell populations. Although they provide impressively efficient sorting, they are costly, mechanically complex, and require large sample volumes and trained personnel for operation and maintenance. In addition, the footprint per unit separation is considerable and they typically require large input populations. Inexpensive devices that rapidly sort live cell, particles and even single molecules would greatly facilitate screening of combinatorial chemical, biochemical or biological libraries taking advantage of the enormous power of in vitro evolution. Moreover, such devices would have wide applications in clinical medicine and basic research. Current systems are also not well suited for use in low gravity environments or impose a significant cost in payload size and weight. Agave BioSystems proposes to develop a miniature flow cytometer/ fluorescent cell sorter (nanoSort) based on a novel micropumping system with an integrated optical waveguide that will eliminate these shortcomings. The microfabricated system will be ideal for use in low gravity environments as well as typical laboratory settings and will be both compact and lightweight.

Principal Investigator:

Greg Baxter
Principal Scientist
5126711369
gtb4@cornell.edu

Business Contact:

Noe Salazar
President
5126711369
nsalazar@agavebio.com
Small Business Information at Submission:

Agave BioSystems, Inc.
PO Box 80010 Austin, TX 78708

EIN/Tax ID:
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No