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Labeless, Reagentless, Biosensor

Award Information

Agency:
Department of Defense
Branch:
Office for Chemical and Biological Defense
Award ID:
40388
Program Year/Program:
1998 / SBIR
Agency Tracking Number:
40388
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Agave BioSystems, Inc.
P.O. Box 100 Ithaca, NY 14850-
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Woman-Owned: No
Minority-Owned: Yes
HUBZone-Owned: Yes
 
Phase 1
Fiscal Year: 1998
Title: Labeless, Reagentless, Biosensor
Agency / Branch: DOD / CBD
Contract: N/A
Award Amount: $100,000.00
 

Abstract:

The preponderance of biosensors under development today rely on labeling reagents such as fluorescent, radioisotopic or enzymatic tags. As a result, the added complexity of these reagents and their incorporation into the detection system has resulted in designs that are difficult to implement or that require significant sample preparation steps before introduction into the detection instrument. While increasing signal, these labels also increase noise, can negatively impact on specificity and overall in the signal-to-noise ratio. In short, the need for reagents by current systems has created significant obstacles to fielding a truly portable, reliable and easy to use biosensor, i.e., one that can be used by the warfighter without significant training or preparation. To meet these needs, Agave BioSystems proposes to develop a truly labeless and reagentless biosensor based upon the optical diffraction of analyte bound to reflective silicon. Key to this effort is the innovative, proprietary microcontact printing technology of Agave BioSystems and its collaborator. This technology allows the precise placement of arrays of biological recognition molecules to form gratings which coupled with optical defraction allows the reagentless detection of multiple targets.

Principal Investigator:

Dr. Carl A. Batt
6072552890

Business Contact:


0
Small Business Information at Submission:

AGAVE BIOSYSTEMS, INC.
117 Devlen Rd Groton, NY 13073

EIN/Tax ID:
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No