This Small Business Innovation Research (SBIR) Phase I project proposes to develop an integrated microchip system for glycosylated hemoglobin (GHb). The approach adapts existing protocols for GHb detection using capillary gel electrophoresis and pulsed amperometric detection. The commercial… More

This Small Business Innovation Research (SBIR) Phase II project aims at developing the next generation of diabetic monitoring devices that will allow the measurement of multiple markers of disease regulation and progression using an innovative lab-on-a-chip technology. The project will develop the… More

DESCRIPTION (provided by applicant): Cardiovascular disease is the number 1 killer in the United States and much of the Western world. Treatment of the disease costs billions of dollars each year and the costs continue to rise exponentially. Many strides have been made toward improving behavioral… More

DESCRIPTION (provided by applicant): Currently, an estimated 8 million Americans have substantial kidney impairment and this number is growing. More people die annually from kidney failure than from either colon cancer, breast cancer, or prostate cancer. Estimated medical and other economic costs of… More

DESCRIPTION (provided by applicant): Cardiovascular disease (CVD) is the number 1 killer in the United States and much of the Western world. Treatment of the disease costs billions of dollars each year and the costs continue to rise exponentially. If consi dered as a separate condition outside of… More

DESCRIPTION (provided by applicant): This Small Business Technology Transfer Phase I project will develop a prototype online perchlorate monitor for a resin bed perchlorate remediation reactor. The device will be have less than 4 ppb limit- of-detection, p rovide results in less than 3 min., and… More

DESCRIPTION (provided by applicant): Perchlorate, ClO4-, is a small highly water soluble anion created by both geogenic and anthropogenic sources. Anthropogenic sources include solid rocket fuel, matches, dyes, paints, airbag inflators, pyrotechnics, flare s, and fertilizers. Human exposure to… More

Biomass is a renewable resource with high potential to achieve cost effective, reliable, and environmentally friendly energy to the American consumer, but yet is still deemed inefficient. First, current methodologies only allow conversion of cellulosic materials into biofuel, leaving energy-rich… More

This Small Business Innovation Research (SBIR) Phase I project will develop a prototype online ion monitor for more efficient and cost effective management of water resources in the power industry. The industry currently lacks instrumentation that can both monitor ions below 10 g/L concentrations… More

The emerging cellulosic-based biofuels industry will benefit national security, lower Green House Gases (GHG) emissions, and bolster the American farmer through a reliable cash crop without necessarily stressing the American food supply. For the biomass industry to become sustainable, it is believed… More