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COMPUTERIZED NONINVASIVE MONITORING OF BRAIN OXYGENATION

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 1R43NS042470-01A1
Agency Tracking Number: NS042470
Amount: $100,000.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: N/A
Solicitation Number: N/A
Timeline
Solicitation Year: N/A
Award Year: 2002
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
ADVANCED BIOENGINEERING TECH 17 INDIAN ROCK RD
WARREN, NJ 07059
United States
DUNS: N/A
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 JOHN MATONICK
 (908) 903-0271
 JMATONICK@YAHOO.COM
Business Contact
 JOHN MATONICK
Phone: (908) 903-0271
Email: JMATONICK@YAHOO.COM
Research Institution
N/A
Abstract

DESCRIPTION (provided by applicant): Stroke continues to be the number three principal cause of death, and one of the leading causes of disability, in the United States. Continued improvements in these statistics requires a better understanding of the functional dynamics of the cerebral vasculature and oxygen utilization of the surrounding tissue during various physiological conditions.We propose a computerized method that affords real time continuous noninvasive measurement and quantitative analysis of the combined hemoglobin saturation levels and auditory evoked potentials during ischemic conditions of the brain. Unique enhancements of the current Near Infrared Spectroscopy (NIRS) technology have been developed along with a Brain Auditory Evoked Potential (BAEP) system.

In Phase I we will demonstrate the feasibility of such an undertaking with animal experiments designed to investigate the capabilities of the novel NIRS system coupled with the BAEPs generated during varying extents of cerebral ischemia.

In Phase II, we will extend this application to further investigate conditions of cerebral ischemia as well as hypoxic states. The long-term goal is to provide a real time noninvasive monitoring capability of brain oxygenation during surgical procedures and cerebral vascular accidents.

* Information listed above is at the time of submission. *

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