A gas-loaded wiggler is proposed as a method for the coupling of intense optical radiation and charged particles to achieve high-gradient acceleration of 100 mev/m or more. the method minimizes the loss of energy due to synchrotron radiation at high particle energies while still achieving high… More

The objective of this project is to develop transition radiators with high average photon flux and to use them as x-ray sources for scientific and technological research. in particular, the company will study the use of these sources for x-ray lithography for the pro- duction of integrated circuits.… More

The objective of the proposed program is to investigate the use of resonance or coherent transition radiation for the identification of high-energy particles. the techniques proposed can be used for particle-mass identification or forbeam diagnostic and monitoring. two devices will be constructed.… More

The purpose of the proposed experiment is to conduct an evaluation of transition radiation for the non-invasive assessment of coronary artery disease in humans. the high brightness and laser-like collimation of transition radiation, make it an ideal source of x-rays for medical applications. recent… More

The objective of the proposed program is to investigate the use of coherent transition radiation to measure the energy of ultra-relativistic charged particles. this research is important in high-energy physics for the detection and identification of these particles. the research can also result in a… More

There is a need for a coronary-artery disease screening method not requiring the risk of an arterial catheter. digital-subtraction radiographs using iodine-k-edge subtraction suffer from low x-ray intensities and require large iodine concentrations precluding non-invasive techniques. brighter x-ray… More

The purpose of this work is to conduct an evaluation of channeling radiation for the noninvasive assessment of coronary artery disease in humans. the high brightness, laser-like collimation, linear polarization, and quasimono- chromaticity of channeling radiation make it an ideal sourceof x-rays for… More

The objective of the proposed research program is to investigate the use of collimating optics with a transition-radiation source to produce a low cost, laboratory scale, intense, focused, soft x ray source for spectroscopy. as has been seen from the rapid rise in the use of synchrotron radiation,… More

We plan to investigate the use of resonance transition radiation to identify ultra-relativistic charged particles. we will look into methods for single and multiple particle identification. by selecting foil thickness and spacing, it is possible to design radiators whose angle of emission increases… More

Current synchrotron-based medical imaging facilities employ narrow (.05 - 1%) bandwidth monochromators to produce monochromatic sources of hard x-rays for dual-energy digitalsubtraction angiography. we have been able to demonstrate that the bandwidth can be increased to 5 to 10% provided that the… More

The objective of the proposed research program is to investigate the use of a novel transition-radiation source to produce a low-cost, laboratory-scale, intense, pulsed x-ray source. by designing transition radiators to emit x rays at the foil material k-shell photoabsorption edge, the x-ray… More

Superlattice channeling radiation is being investigated as an intense, quasi-monochromatic x-ray source. a strained layer superlattice possesses bent planes which alternate direction with each layer of the superlattice crystal. a high energy charged particle which is channeled along a bent plane… More

The objective of this research is to markedly increase the efficiency of production of ozone by gas discharge type ozone generators. currently, the low efficiency of ozone production, 5 to 10 percent of the theoretical maximum with dry air and oxygen feed gas, has limited broader use of this… More

By designing transition radiators such that there is uniform foil thickness and spacing, the angle of emission can be reduced and the brightness of the x-ray source increased. under this contract we will calculate the brightness of this source and compare it to synchrotron emitters. in addition we… More

Performance of optical devices is greatly affected by small surface irregularities. in x-ray optics, for instance, roughness characterized by a root-mean-square height of a few angstroms on a thin film surface can severly affect device performance, and highly sensitive tools are generallyrequired… More

The surface plasmon resonance phenomenon will be explored to develop a quantitative, sensitive, assay system for reproductive hormones of clinical interest. the approach can attain, with relatively inexpensive instrumentation, a sensitivity limit comparable to existing assay methodologies, without… More

Parametric-x-radiation (pxr) is being investigated in phase i of this project as an intense, monochromatic x-ray source. this radiation is highly collimated, has a bandwidth of 0.1% full width at half miximum, and an intensity equal to that of synchroton radiation on a per electron basis. pxr is… More

The objective of the program is to investigate the use of parametric x-ray radiation (PXR) as a tunable, quasimonochromatic x-ray source for mammography. PXR is generated by placing natural, synthetic crystals, or multilayer structures into the path of a relativistic electron beam. The virtual… More

A novel surface phenomenon will be explored for the quantitative detection of nucleic acid hybridization. We will construct a relatively inexpensive instrument, which can attain a sensitivity limit comparable to the existing methodologies, without the use of dyes or radioisotopes. As part of the… More

We will develop a new fiber sensor technology based on detection of SP oscillations with thespecific goal of designing a simple, low-cost, remote optical probe capable of measuring HIV and otherviral antibodies upon direct contact with a suitable biological fluid. The sensor will be capable… More

We will create a novel fiber-optic technique to detect the presence and monitor levels ofenvironmentally harmful gases emitted by utility companies and chemical industries as well as presentin inhabited places. Gas molecules are absorbed into a thin film whose optical properties are thenmonitored by… More

The objective of this research is to explore the feasibility of developing a high intensity uv excimer source for the demanding requirements of the semiconductor manufacturing and materials processing industry. emerging processing technologies not requiring a coherent source including uv wafer… More

The objective of this project is to employ the betatron principle to produce an inexpensive electron accelerator capable of producing 20-50 mev electrons with good beam quality and high-average currents of up to 5-50 mua. in conventional betatrons which have been in existence for over 50 years,… More

Parametric x-radiation (pxr) is proposed as an intense, tunable, monochromatic hard-x-ray source for the detection of explosives. this radiation is highly collimated, has a bandwidth of 0.1, and an intensity equal to that of synchrotron radiation on a per electron basis. pxr generation is achieved… More

The purpose of the proposed work is to design x-ray optics for the collection and redistribution of the annular x-ray cone generated by transition radiation such that a uniform x-ray spot is delivered at high power density to a mask/wafer target. this will increase the power density from the… More

The objective of this research is to explore the feasibility of developing compact, high concentration, ozonegeneration equipment for the demanding requirements of the semiconductor manufacturing and materials processing industry. emerging processing technologies using ozone chemistry have given… More

We will improve microfilter technology with a superior track-etched filter. Microfilters are used ivariety of analytical procedures including the concentration of macromolecules, the sterilization ofpharmaceuticals, and to analyze microbiological impurities. These track-etched filters will be… More

We will develop a new process for sterilizing medical instruments at room temperature. Ourapproach will provide physicians and surgeons with compact equipment capable of sterilizing rigid andflexible endoscopes and other heat sensitive medical instruments in less than 30 minutes. The lack ofa… More

40458 Adelphi Technology, Inc. This project will design two inexpensive, compact betatron-based electron sources: one at 5-MeV and one at 35-MeV. The primary design object of these two sources will be low emittance (¿n

This Small Business Innovation Research Phase I project will develop refractive x-ray lenses for medical, industrial, scientific, and directed-energy applications. Previously, ordinary optical refractive lenses were assumed to not work at x-ray wavelengths because refractive effects were very small.… More

65576 Ionization chambers and photomultiplier tubes are commonly used in nuclear physics and other scientific research due to their sensitivity and energy resolution. However, these detectors provide very poor imaging capabilities. Alternatively, phosphor screens, photoemissive materials, and… More

This Phase I Small Business Innovation Research proposal will develop porous dielectrics as a low-cost, large-area detector for high spatial resolution x-ray detection. An alternative to microchannel plates, porous dielectric electron amplifiers are formed by a thin layer, generally less than 1 mm,… More

The goal of this effort is to develop a large-area, low-cost medical X-ray imager with image quality comparable with state-of-the-art digital medical imagers at a significantly lower X-ray exposure to the patient. The proposed imager will combine two technologies: porous dielectric materials and… More

This Phase I Small Business Innovation Research proposal will develop porous dielectrics as a low-cost, large-area detector for high spatial resolution x-ray detection. An alternative to microchannel plates, porous dielectric electron amplifiers are formed by a thin layer, generally less than 1 mm,… More

DESCRIPTION (Applicant's abstract verbatim): The objective of this proposed research is to construct a prototype neutron microscope capable of imaging biological maternal. By using compound refractive lenses recently developed by Adelphi Technology microscopy is possible… More

This Small Business Innovation Research (SBIR) Phase I project will develop a compact source for lithography. As a synchrotron equivalent, this proposal presents a single-stepper, XUV or soft-x-ray source, which offers high brightness, high collimation, modest operating vacuum, excellent spectrum… More

"The objective of this proposed research is to develop a gamma-ray detector capable of detecting specific atomic species (e.g. N and O) of composite materials such as explosives, nuclear materials and drugs. The detector will detect nuclear resonancefluorescence (NFR) characteristic lines from… More

"This Small Business Innovation Research Phase I project will develop large-area refractive x-ray lenses for medical, industrial, scientific, and directed-energy applications. In prior research and development, Adelphi Technology Inc. has developed compoundrefractive lenses (CRLs) that can focus and… More

70585 There is a need for the conditioning and monochromatizing of neutrons for medical, industrial and scientific purposes. Currently, the most favored techniques for monochromatizing neutron beams are mechanical, reflection, and diffraction methods. However, these methods have only limited… More

Description (provided by applicant): The objective of the proposed research is to construct a prototype narrow-bandwidth x-ray source for mammography using a thin, efficient hybrid radiator driven by a relativistic electron beam of moderate energy and current. The high x-ray yield… More

Description (provided by applicant): The objective of the proposed research is to construct a prototype narrow-bandwidth x-ray source for mammography using a thin, efficient hybrid radiator driven by a relativistic electron beam of moderate energy and current. The high x-ray yield… More

70585S02-II The most favored techniques for monochromatizing neutron beams, needed for medical, industrial and scientific purposes, are mechanical reflection and diffraction methods, both of which have limited efficiency and great cost. Furthermore, neutrons can be used for imaging,… More

70585S02-II The most favored techniques for monochromatizing neutron beams, needed for medical, industrial and scientific purposes, are mechanical reflection and diffraction methods, both of which have limited efficiency and great cost. Furthermore, neutrons can be used for imaging,… More

This Small Business Innovation Research (SBIR) Phase II project aims to develop a sub-micron x-ray tomography scanner capable of providing in-vivo and high resolution images of specimens from mice to bacteria. In this era of molecular medicine, where disease and developmental disorders are being… More

75903-Neutron radiography, which uses nuclear reactors and accelerators as sources of neutrons, has been demonstrated to be an excellent method for imaging high-density, thick objects for the detection of corrosion, voids, and cracks, particular in nuclear power plants. Unfortunately, no high… More

This Small Business Innovation Research (SBIR) Phase II project aims to develop a sub-micron x-ray tomography scanner capable of providing in-vivo and high resolution images of specimens from mice to bacteria. In this era of molecular medicine, where disease and developmental disorders are being… More

75903-Neutron radiography, which uses nuclear reactors and accelerators as sources of neutrons, has been demonstrated to be an excellent method for imaging high-density, thick objects for the detection of corrosion, voids, and cracks, particular in nuclear power plants. Unfortunately, no high… More

The proposed research will demonstrate the technical feasibility of fabricating an effective screening system that will detect explosive materials. The system will be single-sided exposure and detection scheme permitting standoff distances of 1 meter or more. The system will consist of a new,… More

DESCRIPTION (provided by applicant): The goal of this proposal is to develop a nanometer-scale resolution computerized tomographic imaging system for small animal and molecular imaging. This will be achieved by developing a specialized x-ray source designed to work with x-ray compound refractive… More

The objective of the proposed research is to design an inexpensive, compact neutron microscope capable of imaging biological material that can meet specific medical research and clinical needs. One particular clinical application for the thermal or cold neutron microscope that we will address in the… More

DESCRIPTION (provided by applicant): This Small Business Innovation Research Phase 1 project will develop a hard-x-ray microscope capable of producing dark-field images for the detection of colloidal gold particles. Gold colloidal particles are used as labels in the study of antigens and cell and… More

DESCRIPTION (provided by applicant): The goal of this proposal is to develop a nanometer-scale resolution computerized tomographic imaging system for small animal and molecular imaging. This will be achieved by building a system designed to work with x-ray compound refractive lenses. Research and… More

This Small Business Innovation Research Phase I project will develop a fast-neutron detector capable of higher resolution and efficiency than previous detectors. Because fast neutrons are highly penetrating, they have the possibility of imaging and interrogating large, high-density objects.… More

DESCRIPTION (provided by applicant): We propose to develop a commercial neutron source for the treatment of brain and liver cancer based on boron neutron capture therapy (BNCT). Boron-containing compounds are injected into a patient's bloodstream and accumulate in a malignant tumor. When irradiated… More

The accurate detection of neutrons can make invaluable contributions to the physical, chemical, and biological sciences, and the DoE operates neutron user facilities to support these endeavors. This project will build a compound refractive prism (CRP) that refracts and spatially separates neutrons… More

There are no long-lived gamma-ray calibration sources with energies above 3.5 MeV, which is an impediment to the calibration of high-purity-germanium (HPGe) and scintillation detectors used in cutting edge experiments in nuclear physics, astrophysics, and homeland security. In addition, there are… More

A detection system will be fabricated, and tested to demonstrate the detection of vehicle-borne or buried explosives at distances greater of 1 meter or more. The system is comprised of a high-intensity fast-neutron source and an array of gamma-ray detectors that are material specific. The fast… More

A pulsed neutron generator is proposed for the detection of special nuclear material. A recently developed RF-excited plasma neutron generator will be pulsed to produce the activating neutrons whose pulse length is 100 microseconds with a fall time of less than 1 microsecond. High pulse repetition… More

This Small Business Innovation Research Phase II research project will develop a fast-neutron imaging detector capable of high resolution and efficiency. Traditionally, fast neutron detection has required a thick, low resolution scintillator material. The proposed research will instead use… More

A short-pulsed neutron generator is proposed for the detection of concealed high explosives. A recently developed RF-excited plasma neutron generator will be pulsed to produce the activating neutrons whose pulse length is 5-10 ns with a repetition rate of 100 kHz. Using the D-T nuclear reaction, we… More

Refractive lenses can dramatically improve neutron instrumentation in DOE facilities. In previous experiments, compound refractive lenses (CRLs) were shown to be capable of imaging using thermal neutrons. However, a number of problems exist that prevent the full implementation of these lenses: the… More

A pulsed neutron generator is proposed for the detection of special nuclear material. A recently developed microwave-excited plasma neutron generator will be pulsed to produce the activating neutrons whose pulse lengths vary from 100 microseconds to 2 ms with a fall time of less than 1 microseconds.… More

The accurate detection of neutrons can make invaluable contributions to the physical, chemical, and biological sciences, and the DoE operates neutron user facilities to support these endeavors. The utility of prisms for neutron detection has long been established, but a single neutron prism has… More

Small Angle Neutron Scattering (SANS) has been an extremely productive materials science probe for several decades and is used extensively by researchers studying a wide range of subjects, including polymers, ceramics, metals and biological macromolecules and functions. However, it is limited to… More

An improved neutron collection and focusing lens is needed for small angle neutron scatter and neutron microscopy, and increasing flux for thermal neutron capture gamma analysis. Adelphi Technology proposes to design, fabricate, and test a two-dimensional magnetic lens to refract and focus thermal… More