The goal of this research is to devise automated methods of analyzing the auditory brainstem response (abr) when it is recorded using three orthogonal channels. the resulting 3- channel lissajous trajectory (3-clt) shows both linear and planar portions, which will be detected using algorithms tested… More

The goal of this research is to determine the feasibility of combining three-channel recording of the auditory brainstem response (abr) with a stimulus-pairs technique so as to measure the decrement in response that occurs in the relative refractory period (rrp). this method will permit detection of… More

The goal of this research is to implement and test an algorithm that will permit accurate recording of the auditory brainstem response (abr) at very high-repetition rates by extracting the abr from later responses (e.g., the middle latency response). phase i will accomplish the goal of programming… More

Preliminary studies have demonstrated the feasibility of a novel computational scheme which will address critical errors in the present methodology of source localization. These studies will also make it feasible to obtain source location and pattern of activity based on realistic models of the head… More

While auditory evoked responses are often used for objective assessment of hearing, especiallyin infants, such responses do not provide an adequate measure of low-frequency hearing. This, in turn,makes more difficult the selection of a hearing aid appropriate for the patient's hearing… More

This project is intended to provide computational resources to users of Dipole Source Localization(DSL) methods to allow them to decide whether or not their DSL results are distorted by certain errorscalled model misspecification errors. These errors are essentially due to incorrect weighing… More

We will develop a comprehensive, flexible laboratory software system that controls stimuli anddata acquisition in NIH health-related research studies, to meet the needs of research in cognitivepsychology and neurobiology, in terms of both capabilities and convenience. The Phase I workplan ispart of… More

DSL (Dipole Source Localization) is an important advance in evoked potential research because it prinformation on the location of equivalent dipole generators within the brain, and also separates thesimultaneously-active generators. Since evoked responses are used in both research and in the… More

This research relates to evoked response testing of humans. The goal is to develop and test a methorecording the middle-latency auditory evoked-potential, to click or tone-pip stimuli at stimulus rep60 Hz, including 40 Hz. This may provide a test of cortical function which is especially sensitive… More

Our goal is to develop external head shape/skull parameter measurement techniques which will permitconstruction of Boundary Element Method (BEM) head shape models to improve Dipole Source Localizatioprocedures, useful in analyzing brain Event-Related Potentials (ERPs) and magnetoencephalograms… More

Not Available Microvision proposes to provide a preliminary design for a head or helmet-mounted display that permits the tank commander to have greatly increased situational awareness without the use of a periscope and while allowing him/her to remain inside the vehicle. This display is based on… More

DESCRIPTION(Adapted from applicant's abstract): Multiple-channel brain evoked-response data is often recorded from the scalp, either electrically, or magnetically. The analysis of this multi-channel data … More

DESCRIPTION (provided by applicant): The evoked response called the ABR (Auditory Brainstem Response) is affected by nerve compression by acoustic neuromas, but is not presently sensitive enough to detect small tumors. If the ABR could be used to detect tumors, it would reduce overall medical costs… More

DESCRIPTION (provided by applicant): A new method for recovering superposed waveforms when the evoked-response is longer than the interval between stimuli has been recently invented. The new method is called QSD (q-Sequence Deconvolution). QSD can recover brain responses not previously observed… More

DESCRIPTION (provided by applicant): We are developing means to reduce errors in Dipole Source Localization (DSL). DSL is commonly used to analyze brain waves for clinical and research purposes. It is known from our work and the work of others that the models used to compute the DSL are not… More

DESCRIPTION (provided by applicant): This project will study electrical brain-activity measures that may be able to indicate whether or not long-term memory is occurring, under light sedation. The goal is to develop a brain-monitor to be used in the operat ing room to ascertain if a patient's level… More

DESCRIPTION (provided by applicant): This project will develop software for Web-based Compendia , which is defined as a concise, yet comprehensive, organization of a body of knowledge, together with its evaluation. Such Compendia will for a basis for Ou tlined-Knowledge on the Web. The software… More