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Reduction of Burn Progression and Scar Contracture with Cytokine-Neutralizing…

Award Information

Agency:
Department of Defense
Branch:
N/A
Award ID:
Program Year/Program:
2013 / SBIR
Agency Tracking Number:
H122-016-0039
Solicitation Year:
2012
Solicitation Topic Code:
DHP12-016
Solicitation Number:
2012.2
Small Business Information
Washburn Therapeutics, Inc.
6743 Wilkins Ave. Pittsburgh, PA -
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2013
Title: Reduction of Burn Progression and Scar Contracture with Cytokine-Neutralizing Gels
Agency: DOD
Contract: W81XWH-13-C-0050
Award Amount: $150,000.00
 

Abstract:

Washburn Therapeutics Inc. is developing biologically active gels that control inflammation by selectively neutralizing pro-inflammatory cytokines based on a technology being licensed exclusively by the company from Carnegie Mellon University. Preliminary results demonstrated that conjugates of antibodies against tumor necrosis factor-alpha and hyaluronic acid were able to reduce secondary necrosis in a partial-thickness rat burn model by 70%. This SBIR Phase I will focus on treating partial-thickness burns to test of the safety and efficacy of the technology in preventing extensive tissue necrosis following burn and measuring subsequent scar contraction in the rat burn model. The hypothesis of this research program is that prevention of burn progression through local control of inflammatory responses will improve healing outcomes. Early therapeutic intervention could make a significant impact in burn treatment.

Principal Investigator:

Newell R. Washburn
President
(412) 908-1309
newell.washburn@gmail.com

Business Contact:

Newell R. Washburn
President
(412) 908-1309
newell.washburn@gmail.com
Small Business Information at Submission:

Washburn Therapeutics, Inc.
6743 Wilkins Ave. Pittsburgh, PA -

EIN/Tax ID: 300430358
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No