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Development of a Multiplexed Antigen Screening Platform for Detecting Evidence…

Award Information

Agency:
Department of Defense
Branch:
N/A
Award ID:
Program Year/Program:
2012 / SBIR
Agency Tracking Number:
O112-H05-3044
Solicitation Year:
2011
Solicitation Topic Code:
OSD11-H05
Solicitation Number:
2011.2
Small Business Information
ADA Technologies, Inc.
8100 Shaffer Parkway Suite #130 Littleton, CO 80127-4107
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2012
Title: Development of a Multiplexed Antigen Screening Platform for Detecting Evidence of Mycobacterium Tuberculosis Infections
Agency: DOD
Contract: FA8650-12-M-6254
Award Amount: $149,997.00
 

Abstract:

Tuberculosis (TB) is a re-emerging infectious disease threat worldwide. To protect the health of US military personnel, TB screen is required for military personnel at the time of service entrance. However, current TB screening methods TST and IGRA used in military population have their drawbacks in application such as high false positives and being heavily lab dependent. Here ADA Technologies, Inc. (ADA) proposes multiplexed M. tuberculosis (Mtb) antibody screen method based on a sensitive 3-D biomimetic microarray system. In Phase I effort, preliminary feasibility assessment will be performed based on the selection of multiple Mtb-specific antigens that can form composite biomarkers via statistical analysis to achieve optimal detection sensitivity and specificity. The Phase I results would provide justification and guidance for a continued development effort in Phase II, which will create a high-throughput (HTS) and miniaturized platform for TB screen in military populations.

Principal Investigator:

Jian Zhang
Research Scientist
(303) 792-5615
jianz@adatech.com

Business Contact:

Clifton H. Brown, Jr.
President&CEO
(303) 792-5615
cliffb@adatech.com
Small Business Information at Submission:

ADA Technologies, Inc.
8100 Shaffer Parkway Suite #130 Littleton, CO -

EIN/Tax ID: 840984053
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No