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Design Automation Software for Biomimetic Surface Presentation with DNA Origami

Award Information

Agency:
Department of Defense
Branch:
Office for Chemical and Biological Defense
Award ID:
Program Year/Program:
2012 / SBIR
Agency Tracking Number:
C122-103-0003
Solicitation Year:
2012
Solicitation Topic Code:
CBD12-103
Solicitation Number:
2012.2
Small Business Information
Parabon NanoLabs, Inc.
11260 Roger Bacon Drive Suite 406 Reston, VA 20190-5203
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2012
Title: Design Automation Software for Biomimetic Surface Presentation with DNA Origami
Agency / Branch: DOD / CBD
Contract: W911SR-13-C-0019
Award Amount: $150,000.00
 

Abstract:

A development program is proposed for a design automation software package that enables the generation of complex surfaces, with user defined or automated definition of point charge and hydrophobic/hydrophilic properties, using DNA origami as a presentation substrate. Building upon existing software for DNA origami design, this project will result in software able to optimize DNA staples and other origami modifications to achieve target charge and hydration force distributions. The objects to be generated with this software will be able to mimic any of the many surface/surface interactions found in biological or technological applications. Such design software will significantly expand the capabilities of users to produce systems that are capable of highly specific interactions with target macromolecular species.

Principal Investigator:

Steven Armentrout
President&CEO
(703) 689-9689
steve@parabon.com

Business Contact:

Paula Gawthorp-Armentrout
VP&Corporate Secretary
(703) 689-9689
paula@parabon.com
Small Business Information at Submission:

Parabon NanoLabs, Inc.
11260 Roger Bacon Drive Suite 406 Reston, VA -

EIN/Tax ID: 262194625
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No