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Design Automation Software for DNA-Based Nano-Sensor Architectures
- Small Business Information
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Woman-Owned: NoMinority-Owned: NoHUBZone-Owned: No
- Phase 2
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Fiscal Year: 2012Title: Design Automation Software for DNA-Based Nano-Sensor ArchitecturesAgency / Branch: DOD / OSDContract: W911NF-12-C-0060Award Amount: $750,000.00
Abstract:
A continuing and growing threat to US military personnel and civilians is exposure to toxic chemicals and pathogens. Useful detection systems exist, but it remains imperative to investigate new technologies that have the potential to significantly improve the cost, sensitivity, and size of sensor devices. A promising technology that may achieve these goals is DNA-based nono-sensors. In order for this technology to become viable, it needs automated assay design software. To achieve this, Celadon will collaborate with Dr. David Mathews, an expert in the computation of nucleic acid structures; and with Dr. Jason Kahn, an expert in dna structure and topology and nucleic acid thermodynamics. In Phase I, our team computed databates of optimal helices and loops; developed a heuristic algorithm that obviates the need to evaluate an entire structure; developed a new algorithm for design of psuedo knots, among other deliverables. In Phase II, we will nxnxnxnxnxnxnxnxnSmall Business Information at Submission:Research Institution Information:Celadon Laboratories, Inc.
6525 Belcrest Rd Hyattsville, MD 20782-2003EIN/Tax ID: 522223222DUNS: N/ANumber of Employees:Woman-Owned: NoMinority-Owned: NoHUBZone-Owned: NoUniv of Rochester+Univ.of Maryland
518 Hylan Building
PO Box 270140
Rochester, NY 14627-0140Contact: Tammie MartinContact Phone: (585) 275-4031
Award Information
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Agency: Department of Defense |
Branch: Office of the Secretary of Defense |
Award ID: |
Program Year/Program: 2012 / STTR |
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Agency Tracking Number: O2-1274 |
Solicitation Year: 2010 |
Solicitation Topic Code: OSD10-T003 |
Solicitation Number: 2010.B |