Artificial Tissue Matrices for Bone Repair

The motivation for this research project is to develop nanocomposite material for biomimetic bone repair material that meets all the requirements of solicitation N102-179. This project will provide the means to produce an advanced composite of materials with known efficacy to leverage the mechanical and physiological properties of each. Once validated, the material will provide a bone repair scaffold with: fabrication with precise porosity; will be biomimetic; durable and capable of surgical manipulation; non-toxic; resorbable; cost effective; and the system will be able to produce large quantities of material. The goal is to develop an innovative material and for a variety of custom implants for a wide range of military and civilian bone injuries due to trauma and/or disease. The scaffold will be unique in its construction as it combines the nanocomposite structure with an ingrowth promotion material.