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Clinical Reagents for Peripheral Blood Stem Cells

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
29502
Program Year/Program:
1997 / SBIR
Agency Tracking Number:
29502
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
QUALITY BIOLOGICAL, INC.
QUALITY BIOLOGICAL, INC. 7581 LINDBERGH DRIVE GAITHERSBURG, MD 20879
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Woman-Owned: Yes
Minority-Owned: Yes
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1997
Title: Clinical Reagents for Peripheral Blood Stem Cells
Agency: HHS
Contract: 1 R43 HL53804-01,
Award Amount: $750,000.00
 

Abstract:

We will develop fully defined, serum-free culture reagents, which contain no components of non- humwhich can be produced under completely controlled and reproducible pharmaceutical standards, and whiwith recombinant human hematopoietic factors will successfully support the generation and expansionprogenitor cells in-vitro from normal human marrow or blood mononuclear cells in short-term suspensidefine, develop and carry out initial preclinical evaluation of fully-defined, serum-free culture recomponents of non-human origin, to be used for culture of normal human hematopoietic progenitor cellbe to use successful serum-free reagents that have been shown to support hematopoietic stem cell expcontain components of non-human origin which will be sequentially replaced with components that areapproved. Development of these tissue culture reagents will focus on a specific clinical applicationand expansion of late neutrophil progenitors for infusion into patients undergoing autologous bone mblood stem cell transplantation in order to prevent or abate profound neutropenia in these patients.

Principal Investigator:

Ronald Brown
30140

Business Contact:

Small Business Information at Submission:

Quality Biological, Inc.
7581 Lindbergh Drive Gaithersburg, MD 20879

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No