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Company Information:

Name: NUVOGEN RESEARCH, LLC
Address: PO Box 64326
Tucson, AZ 85728-0000
Located in HUBZone: No
Woman-Owned: No
Minority-Owned: No
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $1,529,145.00 9
SBIR Phase II $2,114,494.00 4

Award List:

N/A

Award Year / Program / Phase: 2000 / SBIR / Phase I
Agency: NSF
Principal Investigator: Richard Kris
Award Amount: $100,000.00

N/A

Award Year / Program / Phase: 2001 / SBIR / Phase I
Agency: NSF
Principal Investigator: Christopher Montgomery
Award Amount: $0.00

N/A

Award Year / Program / Phase: 2001 / SBIR / Phase II
Agency: NSF
Principal Investigator: Christopher Montgomery
Award Amount: $500,000.00

HIGH-THROUGHPUT DNA MICROARRAYS FOR OSTEOBLASTS

Award Year / Program / Phase: 2002 / SBIR / Phase I
Agency: HHS
Principal Investigator: Richard M. Kris
Award Amount: $98,226.00
Abstract:
A quantitative high-throughput gene chip assay, ArrayPlateTM, based on nuclease protection has been developed for drug discovery. We will use this technology to develop an assay that can measure in a single well of a 96-well microplate, the differentiation of stem cells to osteoblasts or myoblasts… More

HIGH-THROUGHPUT DNA MICROARRAYS FOR INFLAMMATION

Award Year / Program / Phase: 2002 / SBIR / Phase I
Agency: HHS
Principal Investigator: Stephen Felder
Award Amount: $592,698.00
Abstract:
A quantitative high-throughput gene chip assay, ArrayPlateTM, based on nuclease protection has been developed for drug discovery. We will use this technology to develop two novel assays designed to screen for compounds that affect the expression of transcription factors and regulated… More

SBIR Phase II: Development and Manufacture of High-Density Plate Washer

Award Year / Program / Phase: 2003 / SBIR / Phase I
Agency: NSF
Principal Investigator: Richard M. Kris, Dr
Award Amount: $100,000.00
Abstract:
This Small Business Innovation Research (SBIR) Phase II project aims to develop a plate washer capable of washing very high-density plates, such as 1536 well plates, for ELISA and high-throughput screening assays. Currently, there are automated plate washers for 96 and 384 well plates, but there … More

High-Throughput DNA Microarrays for Osteoblasts

Award Year / Program / Phase: 2004 / SBIR / Phase II
Agency: HHS
Principal Investigator: Richard M. Kris
Award Amount: $749,906.00
Abstract:
DESCRIPTION (provided by applicant): This Phase II grant proposes to screen for 100,000 compounds that stimulate differentiation of adult human mesenchymal stem cells using a multiple mRNA assay, in 96-well plates. The assay quantifies induction of genes that signal differentiation to osteoblasts,… More

SBIR Phase II: Development and Manufacture of High-Density Plate Washer

Award Year / Program / Phase: 2005 / SBIR / Phase II
Agency: NSF
Principal Investigator: Richard M. Kris, Dr
Award Amount: $500,000.00
Abstract:
This Small Business Innovation Research (SBIR) Phase II project aims to develop a plate washer capable of washing very high-density plates, such as 1536 well plates, for ELISA and high-throughput screening assays. Currently, there are automated plate washers for 96 and 384 well plates, but there … More

Natural Product Screening for Prostate Cancer Therapeutics Using Gene Expression

Award Year / Program / Phase: 2008 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $162,191.00
Abstract:
DESCRIPTION (provided by applicant): In Phase I, newly available natural product extracts will be tested to find compounds that specifically target genes that are critical for the androgen receptor pathway of growth stimulation in recurrent prostate cancer s. This is important because the androgen… More

Discovery of Compounds to Inhibit Cancer EMT Genes in Order to Target Metastasis

Award Year / Program / Phase: 2009 / SBIR / Phase I
Agency: HHS
Principal Investigator: Stephen Felder
Award Amount: $146,030.00
Abstract:
DESCRIPTION (provided by applicant): The overall objective of the work proposed in this grant is to find novel drugs that help to prevent metastasis. In Phase I, newly available natural product extracts will be tested to find compounds that specifically ta rget genes that are critical for the… More

SBIR Phase I:Gene signature screening for Pancreatic Cancer Therapeutics from Sonoran Desert extracts

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: NSF
Principal Investigator: Richard M. Kris, ScD
Award Amount: $180,000.00
Abstract:
This Small Business Innovation Research (SBIR) Phase I project is designed to discover compounds from a unique Natural Products Library that block the altered patterns of gene expression seen in pancreatic cancer. The extract and fraction library to be screened is from Dr. Gunatilaka at the… More

SBIR Phase I: A Novel Therapeutic for Hormone Refractory Prostate Cancer

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: NSF
Principal Investigator: Stephen Felder
Award Amount: $150,000.00
Abstract:
This Small Business Innovation Research (SBIR) Phase I project will help develop the first effective therapy for late stage hormone refractory Prostate Cancer (PCa). These late stage tumors rely on the Androgen Receptor (AR) pathway, but do not require androgen. Genetic changes allow tumors to use… More

SBIR Phase II: Gene signature screening for Pancreatic Cancer Therapeutics from Sonoran Desert extracts

Award Year / Program / Phase: 2012 / SBIR / Phase II
Agency: NSF
Principal Investigator: Richard M. Kris
Award Amount: $364,588.00
Abstract:
This Small Business Innovation Research (SBIR) Phase II project is to address the high lethality of pancreatic cancer. Screening has begun with Phase IB funding, of natural products from the Sonoran Desert that have produced other promising drug candidates, testing effects on human pancreatic cancer… More