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Company Information:

Company Name: LNKCHEMSOLUTIONS
City: LINCOLN
State: NE
Zip+4: -
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $1,721,113.00 9
SBIR Phase II $3,046,001.00 3
STTR Phase I $396,413.00 2

Award List:

Nano- and Micro-Encapsulation of Food Additives and Agrochemicals (SBIR Phase I)

Award Year / Program / Phase: 2003 / SBIR / Phase I
Agency: USDA
Principal Investigator: Rajinder Gill
Award Amount: $75,000.00
Abstract:
NON-TECHNICAL SUMMARY: General methods to produce uniform capsules with well-defined and controllable shell thickness and diameter, especially at the nano- and micro-scale, are in great demand for controlled and timed release of drugs, agrochemicals, nutraceuticals, and probiotics. The proposed… More

Novel Nanofiber-reinforced All-ceramic Dental Materials

Award Year / Program / Phase: 2003 / SBIR / Phase I
Agency: HHS
Principal Investigator: Gustavo F. Larsen
Award Amount: $100,000.00
Abstract:
DESCRIPTION: Novel continuous, non-woven oxide nanofibers will be used to design, produce and test a new class of allceramic materials for restorative Dental applications. The working hypothesis is that these new nanofiber/glass systems will be of significantly higher mechanical quality than… More

SBIR Phase II: Nano- and Micro-Encapsulation of Food Additives

Award Year / Program / Phase: 2004 / SBIR / Phase II
Agency: USDA
Principal Investigator: Gustavo Larsen
Award Amount: $296,000.00
Abstract:
Micro- and nano-encapsulation (one nanometer = 0.000000001 meter) of food additives is an active R&D area. The release characteristics and protective properties of the encapsulant need to be tailored to specific industrial needs on a case-by-case basis. Nanotechnoly strategies as the one proposed in… More

SBIR Phase I: Powder Porcessing Routes for Making Submicron Hydrotalcite and Zirconia-Glass Materials

Award Year / Program / Phase: 2004 / SBIR / Phase I
Agency: NSF
Principal Investigator: Gustavo Larsen, PI
Award Amount: $100,000.00
Abstract:
This Small Business Innovation Research (SBIR) Phase I project is a feasibility study to produce two-submicron inorganic powders via solvent-free processing routes. One of the materials is the anionic clay known as hydrotalcite, which is used as an antacid and a PVC additive. The other material is… More

Micro/Nano-Encapsulation of Partial Oxidation Biocatalysts

Award Year / Program / Phase: 2005 / SBIR / Phase I
Agency: DOE
Principal Investigator: Gustavo F. Larsen, Dr.
Award Amount: $99,999.00
Abstract:
78011S Many industrial liquid-phase catalytic processes that require the use of some kind of active species (e.g. sensors, biosensors, chelating agents, and chemical traps) cannot be ¿heterogeneized¿ without significantly penalizing chemical activity and/or selectivity. Biphasic liquid media… More

Submicron Particles and Fibers for Toxicological Studies

Award Year / Program / Phase: 2005 / SBIR / Phase I
Agency: HHS
Principal Investigator: Gustavo F. Larsen
Award Amount: $376,119.00
Abstract:
DESCRIPTION (provided by applicant): This Phase I SBIR program is aimed at initiating a business venture dedicated to the manufacturing of nanoparticulates for toxicology research. The rate of nanotechnology R&D growth in the commercial, academic, and private sectors, appears to be outpaced only by… More

Nanoengineered Encapsulation of Enzyme Chiral Catalysts and Other Proteins in Their Native State

Award Year / Program / Phase: 2006 / SBIR / Phase II
Agency: DOE
Principal Investigator: Gustavo F. Larsen, Dr.
Award Amount: $750,000.00
Abstract:
The commercial opportunities for products based on delicate biomolecules, such as enzymes and therapeutic proteins, are growing at a strong pace. However, many proteins of great commercial value, including enzymes, undergo loss of function on encapsulation, when approaches based on high-shear… More

SBIR Phase I: Catalytic Traps for Capture of Gas-Phase Toxic Linear Molecules

Award Year / Program / Phase: 2006 / SBIR / Phase I
Agency: NSF
Principal Investigator: Gustavo Larsen, Dr
Award Amount: $100,000.00
Abstract:
This Small Business Innovation Research (SBIR) Phase I project will explore the use of a material comprising a fibrous substrate and an inorganic adsorbent/catalytic coating for removal of toxic small linear molecules from smoke. Phase I research will focus on identification of an efficient… More

STTR Phase I: Nanoengineered Encapsulation of Therapeutics

Award Year / Program / Phase: 2006 / STTR / Phase I
Agency: NSF
Research Institution: Argonne National Lab
Principal Investigator: Gustavo Larsen, Dr
Award Amount: $100,000.00
RI Contact: Luis Nunez
Abstract:
This Small Business Technology Transfer (STTR) Phase I project is a feasibility study for the design of true core-shell type nonocapsules for drug delivery. The research will focus on strategies aimed at controlling the nanostructure and chemistry of the capsules, and also on ways to design… More

Nanoparticles and Nanocapsules for Glioma Targeting

Award Year / Program / Phase: 2008 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $400,001.00
Abstract:
DESCRIPTION (provided by applicant): LNK Chemsolutions LLC collaborates with researchers from the University of Chicago to develop nanocapsule technology for enhanced delivery to gliomas. Preliminary results are particularly encouraging in that the nanocap sules display very good transport in… More

Development of New Hemostatic Dressings

Award Year / Program / Phase: 2009 / SBIR / Phase I
Agency: HHS
Principal Investigator: Ruben Spretz
Award Amount: $399,994.00
Abstract:
DESCRIPTION (provided by applicant): A multidisciplinary team of researchers seeks to develop novel and economically feasible implantable hemostatic dressings for severe (e.g. arterial) bleeding. Key features of the device under development are its excelle nt pliability, biocompatibility, and… More

Improved Formulations to Enhance Bio-availability for Antisense Therapeutics

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency / Branch: DOD / CBD
Principal Investigator: Luis Nunez, Chief Technology Officers
Award Amount: $70,000.00
Abstract:
In general, many biological and chemical agents affect the lungs directly or indirectly, even if the respiratory system is not the primary target organ of a military or terrorist attack. Both in the case of military and civilian attacks the lung can be one of the first organs affected by a chemical… More

Nanoparticles and Nanocapsules for Glioma Targeting

Award Year / Program / Phase: 2011 / SBIR / Phase II
Agency: HHS
Principal Investigator: Ruben Spretz – 402-416-1811
Award Amount: $2,000,001.00
Abstract:
DESCRIPTION (provided by applicant): Malignant gliomas represent a heterogeneous family of tumors that are poorly responsive to current treatments. A major obstacle to the effective management of these lesions involves the difficulty in delivering adequateconcentrations of therapeutics to the tumor… More

Development of Ultrafine Particles for Intranasal Delivery of Antipsychotics

Award Year / Program / Phase: 2012 / STTR / Phase I
Agency: HHS
Research Institution: UNIVERSITY OF CHICAGO
Principal Investigator: Sandra E. Noriega – 402-416-1811
Award Amount: $296,413.00
RI Contact:
Abstract:
DESCRIPTION: The goal of the proposed project is to develop a biocompatible ultrafine particle-based vector system for the intranasal delivery of clozapine for the pharmacological therapy of treatment- resistant schizophrenic disorders and their associatedsuicidal behavior. The rationale behind the… More