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SBIR Phase II: Immunological Tools for Trimetasphere Fullerenes

Award Information
Agency: National Science Foundation
Branch: N/A
Contract: 0724380
Agency Tracking Number: 0610979
Amount: $499,955.00
Phase: Phase II
Program: SBIR
Solicitation Topic Code: BT
Solicitation Number: NSF 05-605
Timeline
Solicitation Year: 2005
Award Year: 2007
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
1 Riverside Circle Suite 400
Roanoke, VA 24016
United States
DUNS: 627132913
HUBZone Owned: Yes
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Roger VanTassell
 MS
 (540) 961-4502
 vantassellr@lunainnovations.com
Business Contact
 Roger VanTassell
Title: MS
Phone: (540) 961-4502
Email: vantassellr@lunainnovations.com
Research Institution
N/A
Abstract

This Small Business Innovation Research (SBIR) Phase II research develops antibodies and immunoassays for studying therapeutics based on carbon-based nanomaterials. This research will expand the immunological tools developed in Phase I to focus on detailed characterization of anti-fullerene antibodies and validate and down-select immunoassays and reagents for validated commercial formats. Commercial formats will include enzyme-linked, immunosorbant assays (ELISAs) for medical and environmental applications, neutralization schemes for mitigating potential toxicity of fullerene/nanotubes and biosensors platform for long-term monitoring systems. Biosensor platforms based on fullerene antibodies as affinity ligands will include the quartz crystal microbalance and surface acoustic waveguide. The broader impacts will be to provide a full spectrum of immunological tools for studying the medically-related nanomaterials and monitoring nanowaste by-products during manufacturing processes. These will be new to the marketplace and enable monitoring of the use of products
based on these nanomaterials to asssure their safe application.

* Information listed above is at the time of submission. *

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