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Quantitative DCS Monitor for Blood and Tissue

Award Information
Agency: Department of Defense
Branch: Navy
Contract: N00024-04-C-4121
Agency Tracking Number: N032-0310
Amount: $99,985.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: N03-221
Solicitation Number: 2003.2
Timeline
Solicitation Year: 2003
Award Year: 2004
Award Start Date (Proposal Award Date): 2004-01-29
Award End Date (Contract End Date): 2004-12-02
Small Business Information
2851 Commerce Street
Blacksburg, VA 24060
United States
DUNS: 627132913
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Joseph Heyman
 Principal Investigator
 (757) 224-0687
 heymanj@lunainnovations.com
Business Contact
 Garnett Linkous
Title: Chief Administrative Offi
Phone: (540) 953-4274
Email: linkousg@lunainnovations.com
Research Institution
N/A
Abstract

Luna Innovations in partnership with Virginia Commonwealth University (Dr. Spiess), the Mayo Clinic (Dr. Greenleaf) and Lockheed Martin Orincon (Mr. Sevick) will determine the feasibility of detection of bubble emboli in both blood and tissue in phantoms, animals and humans. The study will include an analysis of current equipment and algorithms. A breakthrough technology based on nonlinear ultrasonics will be explored for use in tissue and blood and compared with a pulse-echo system developed by Orincon. The results of the study will create a new class of DCS instruments using the optimum elements of pulse-echo and radiation pressure. The Phase I will provide validation of the concept at normal atmospheric pressure along with system designs to be brought to practical demonstration in the Phase II on animals and humans in hyperbaric chambers. The resulting system will be easy to use and provide quantitative, objective measures of bubble emboli, assessment of bubble sizes, and levels of bubble density in both tissue and blood.

* Information listed above is at the time of submission. *

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