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Quantitative DCS Monitor for Blood and Tissue
Title: Principal Investigator
Phone: (757) 224-0687
Email: heymanj@lunainnovations.com
Title: Chief Administrative Offi
Phone: (540) 953-4274
Email: linkousg@lunainnovations.com
Luna Innovations in partnership with Virginia Commonwealth University (Dr. Spiess), the Mayo Clinic (Dr. Greenleaf) and Lockheed Martin Orincon (Mr. Sevick) will determine the feasibility of detection of bubble emboli in both blood and tissue in phantoms, animals and humans. The study will include an analysis of current equipment and algorithms. A breakthrough technology based on nonlinear ultrasonics will be explored for use in tissue and blood and compared with a pulse-echo system developed by Orincon. The results of the study will create a new class of DCS instruments using the optimum elements of pulse-echo and radiation pressure. The Phase I will provide validation of the concept at normal atmospheric pressure along with system designs to be brought to practical demonstration in the Phase II on animals and humans in hyperbaric chambers. The resulting system will be easy to use and provide quantitative, objective measures of bubble emboli, assessment of bubble sizes, and levels of bubble density in both tissue and blood.
* Information listed above is at the time of submission. *