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Company Information:

Company Name: HEMOSHEAR, LLC
City: CHARLOTTESVILLE
State: VA
Zip+4: -
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $357,616.00 2
SBIR Phase II $4,293,883.00 1

Award List:

Genome-wide profiling of human vascular response to oxidized lipoprotreins

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: HHS
Principal Investigator: Brett R. Blackman
Award Amount: $166,830.00
Abstract:
DESCRIPTION (provided by applicant): Atherosclerosis is a vascular inflammatory disease characterized by dramatic changes in endothelial cell (EC) and smooth muscle cell (SMC) phenotypes. The progression of atherosclerosis is dependent on interactions bet ween vascular cells (EC/SMC), regional… More

Hemodynamic Co-Culture Liver Model for Drug Discovery and Assessment

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: HHS
Principal Investigator: Brett R. Blackman – 434-872-0198
Award Amount: $190,786.00
Abstract:
DESCRIPTION (provided by applicant): Drug developers desperately need better tools in the laboratory to improve the 90% failure rate of drugs in clinical trials. Liver toxicity is still the leading cause of drug failure, despite extensive preclinical testing in surrogate animal species. HemoShear… More

Creating a predictive vascular system for early development

Award Year / Program / Phase: 2011 / SBIR / Phase II
Agency: HHS
Principal Investigator: Brett R. Blackman – 434-872-0198
Award Amount: $4,293,883.00
Abstract:
DESCRIPTION (provided by applicant): The frequent inability of in vitro assays and animal models to accurately predict human response to a new drug candidate results in costly drug development failures. HemoShear has developed a platform technology for biodiscovery and drug pharmacology screening… More