THIS STUDY IS DESIGNED TO DEVELOP AND EVALUATE A METHOD OF REPLACING A HOLLOW VISCUS WITH A PROSTHESIS THAT ALLOWS PRIMARY MUCOSAL HEALING AND INCORPORATION OF THE PROSTHETIC INTO THE HEALING PROCESS.

Award Information

Agency: Department of Health and Human Services

Branch: N/A

Contract: N/A

Agency Tracking Number: 4876

Amount: $47,000.00

Phase: Phase I

Program: SBIR

Solicitation Topic Code: N/A

Solicitation Number: N/A

Timeline

Solicitation Year: N/A

Award Year: 1986

Award Start Date (Proposal Award Date): N/A

Award End Date (Contract End Date): N/A

Small Business Information

Deseret Research Company Inc

520wakara Way

Salt Lake City, UT 84108

United States

DUNS: N/A

HUBZone Owned: No

Woman Owned: No

Socially and Economically Disadvantaged: No

Principal Investigator

Name: RICHARD E HOFFER
Title: PRINCIPAL INVESTIGATOR
Phone: (801) 584-3232

Business Contact

Phone: () -

Research Institution

N/A

Abstract

THIS STUDY IS DESIGNED TO DEVELOP AND EVALUATE A METHOD OF REPLACING A HOLLOW VISCUS WITH A PROSTHESIS THAT ALLOWS PRIMARY MUCOSAL HEALING AND INCORPORATION OF THE PROSTHETIC INTO THE HEALING PROCESS. HEALING OF A FULL THICKNESS ISOLATED BOWEL SEGMENT TO 2 TYPES OF A HOLLOW VISCUS PROSTHESIS WILL BE EVALUATED IN DOGS. BOTH TYPES OF PROSTHESIS WILL CONSIST OF AN OUTER RIGID MESH AND A BIO- DEGRADABLE MIDDLE LAYER. THE TYPE A PROSTHESIS WILL HAVE ANINNER IMPERVIOUS LAYER, THE TYPE B PROSTHESIS WILL NOT. THEPROSTHESES WILL BE EVALUATED AT VARIOUS POSTIMPLANTATION TIMES OF UP TO AND INCLUDING 60 DAYS. EVALUATION OF HEALINGPATTERNS OF THE PROSTHESES AND MUCOSAL REGENERATION, INFECTION, CONNECTIVE TISSUE INGROWTH, REJECTION, AND STRICTURE WILL BE PERFORMED BY GROSS EXAM AND LIGHT MICROSCOPY.

* Information listed above is at the time of submission. *

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THIS STUDY IS DESIGNED TO DEVELOP AND EVALUATE A METHOD OF REPLACING A HOLLOW VISCUS WITH A PROSTHESIS THAT ALLOWS PRIMARY MUCOSAL HEALING AND INCORPORATION OF THE PROSTHETIC INTO THE HEALING PROCESS.