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Company Information:

Company Name: SEACHANGE PHARMACEUTICALS, INC.
City: SAN JOSE
State: CA
Zip+4: 95128-2532
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $452,741.00 2

Award List:

Drug Repurposing using Pharmacological Networks

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: HHS
Principal Investigator: Michael J. Keiser
Award Amount: $202,500.00
Abstract:
DESCRIPTION (provided by applicant): Three ideas motivate this project. First, bioactive small molecules often act on multiple targets- sometimes this polypharmacology is key to their efficacy, sometimes it is the source of unwanted side-effects, rarely is it entirely absent. Second, these… More

Calculating target bias in small molecules for library design

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: HHS
Principal Investigator: Michael J. Keiser – 415-937-1732
Award Amount: $250,241.00
Abstract:
DESCRIPTION (provided by applicant): Goals: The goal is to develop a computational system to predict the targets toward which small molecules are biased. The tool will optimize biased libraries, prioritize them for testing against particular targets, identify targets in phenotypic screens, and allow… More