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Company Information:
Name:
SEACHANGE PHARMACEUTICALS, INC.
Address:
2806 UNION ST, APT 3
SAN FRANCISCO, CA 94123-
SAN FRANCISCO, CA 94123-
Located in HUBZone:
No
Woman-Owned:
No
Minority-Owned:
No
URL:
N/A
Phone:
N/A
Award Totals:
Award List:
Drug Repurposing using Pharmacological Networks
Award Year / Program / Phase:
2010 / SBIR / Phase I
Agency:
HHS
Principal Investigator:
Michael J. Keiser
Award Amount:
$202,500.00
Abstract:
DESCRIPTION (provided by applicant): Three ideas motivate this project. First, bioactive small molecules often act on multiple targets- sometimes this polypharmacology is key to their efficacy, sometimes it is the source of unwanted side-effects, rarely
is it entirely absent. Second, these… More
Calculating target bias in small molecules for library design
Award Year / Program / Phase:
2011 / SBIR / Phase I
Agency:
HHS
Principal Investigator:
Michael J. Keiser – 415-937-1732
Award Amount:
$250,241.00
Abstract:
DESCRIPTION (provided by applicant): Goals: The goal is to develop a computational system to predict the targets toward which small molecules are biased. The tool will optimize biased libraries, prioritize them for testing against particular targets, identify targets in phenotypic screens, and allow… More