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Company Information:

Company Name: PROLYNX, LLC
City: San Francisco
State: CA
Zip+4: 94117-3851
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $443,608.00 3

Award List:

Releasable site-specific attachment of macromolecules to therapeutic peptides

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: HHS
Principal Investigator: Gary W. Ashley
Award Amount: $143,958.00
Abstract:
DESCRIPTION (provided by applicant): Many potent and specific peptides suffer problems of short or sub-optimal duration. A possible solution to such problems involves conjugation to macromolecules such as polyethylene glycol (PEG) that are slowly eliminate d from the body, and thus prolongs the… More

Releasable attachment of drugs to PEGylated dendrimers

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: HHS
Principal Investigator: Daniel V. Santi
Award Amount: $149,650.00
Abstract:
DESCRIPTION (provided by applicant): We are developing a platform technology that allows predictable, controlled release of drugs from macromolecule-drug conjugates. In one current format, PEG of sufficient size to have prolonged blood circulation times is attached to the drug by linkers designed… More

SBIR Phase I: Controlled Drug Release from and Degradation of PEG-Hydrogels

Award Year / Program / Phase: 2013 / SBIR / Phase I
Agency: NSF
Principal Investigator: Gary W. Ashley
Award Amount: $150,000.00
Abstract:
This Small Business Innovation Research Phase I project seeks to develop novel hydrogel drug-delivery systems. We have developed linkers for drug conjugation to circulating macromolecules that release the native drug by beta-eliminative cleavage at predictable rates with half-lives spanning hours to… More