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Company Information:

Company Name: BIOO SCIENTIFIC CORPORATION
City: AUSTIN
State: TX
Zip+4: 78744-3202
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: (512) 707-8993

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $2,006,931.00 13
SBIR Phase II $1,349,695.00 3

Award List:

Engineered polypeptides for improved antibody production

Award Year / Program / Phase: 2007 / SBIR / Phase I
Agency: HHS
Principal Investigator: Jun J. Wang
Award Amount: $287,420.00
Abstract:
DESCRIPTION (provided by applicant): The overall goal of this proposal is to develop a new cost-effective method for the production of high-purity polyclonal antibodies. Polyclonal antibodies are important reagents used worldwide for antigen detection and purification in basic research as well as… More

SBIR Phase I: Improved in Vivo Delivery of SiRNA

Award Year / Program / Phase: 2008 / SBIR / Phase I
Agency: NSF
Principal Investigator: Lance P. Ford, PhD
Award Amount: $100,000.00
Abstract:
This Small Business Innovation Research (SBIR) Phase I research project aims to develop an improved method for the delivery of small inhibitory ribonucleic acids (siRNA) into cells. The proposed methodology will utilize chemically induced immuno-conjugates or direct linking of siRNAs to antibodies… More

Rapid enzyme-based assays to detect banned substances in food

Award Year / Program / Phase: 2008 / SBIR / Phase I
Agency: USDA
Principal Investigator: Joseph Wang, CEO
Award Amount: $80,000.00
Abstract:
It is important to test the food supply for known toxic or banned substances which can impinge public safety. While a number of high-throughput tests have been developed to screen the food supply for higher molecular weight banned substances, it has been difficult to develop methods to… More

Improved in vivo delivery of siRNA

Award Year / Program / Phase: 2008 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $172,375.00
Abstract:
DESCRIPTION (provided by applicant): The overall goal of this proposal is to develop novel reagents to efficiently deliver functional siRNA into animals for gene silencing experiments. Pharmaceutical and biotechnology companies are actively testing siRNAs as therapeutic agents and to validate drug… More

Assay for rapid Poly(A) Tail length determination

Award Year / Program / Phase: 2008 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $176,218.00
Abstract:
DESCRIPTION (provided by applicant): One of the major underlying factors for the significant broad impact of molecular biology on biomedical research is the generation of effective and highly reproducible assay kits to measure fundamental properties of ge ne expression. One area of molecular… More

TOPIC 229: DEV. OF MOLECULAR PHARMACODYNAMIC ASSAYS FOR TARGET

Award Year / Program / Phase: 2008 / SBIR / Phase I
Agency: HHS
Principal Investigator: Marianna M. Goldrick
Award Amount: $147,500.00
Abstract:
The research will result in new kits for quantitative detection and monitoring of hypoxia inducible factor-1 alpha (Hif-1a), a promising cellular target protein for pharmacological intervention. During the Phase 1 project, monoclonal antibodies will be dev eloped and used to create highly sensitive… More

SBIR Phase II: Improved in Vivo Delivery of SiRNA

Award Year / Program / Phase: 2009 / SBIR / Phase II
Agency: NSF
Principal Investigator: Lance P. Ford, PhD
Award Amount: $500,000.00
Abstract:
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Small Business Innovation Research (SBIR) Phase II project will develop technologies that optimize the use of RNA interference (RNAi) in animals. RNAi is an invaluable tool for characterizing gene… More

Rapid enzyme based detection of toxins in food.

Award Year / Program / Phase: 2009 / SBIR / Phase II
Agency: USDA
Principal Investigator: Joseph Krebs, Director
Award Amount: $349,695.00
Abstract:
The safety of the public food supply is an emerging and important public health issue in the United States. Recent, widely-reported food and feed contaminations by pathogens and banned substances such as melamine have fueled an increased demand for improved assays to screen and protect the food… More

Sequential injection enzymatic assay for melamine detection in food.

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: USDA
Principal Investigator: Joseph Krebs, Director
Award Amount: $80,000.00
Abstract:
Protecting the integrity of the nation's food from contamination by toxins is a very serious challenge for our country. Melamine, in particular, is a toxic substance which has recently emerged as a serious threat to the safety of the U.S. food supply. Recent, widely-reported food and feed… More

SBIR Phase I: Biomolecular Detection of microRNA

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: NSF
Principal Investigator: Masoud Toloue
Award Amount: $150,000.00
Abstract:
This Small Business Innovation Research (SBIR) Phase I project proposes to examine high throughput methods to quantify intacellular microRNA (miRNA) concentrations in cells that have shown to be associated with normal physiological processes as well as diseases including cancer. Currently, there are… More

Development of a novel assay for the analysis of newly synthesized RNA

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: HHS
Principal Investigator: Lance P. Ford – 512-707-8993
Award Amount: $177,693.00
Abstract:
DESCRIPTION (provided by applicant): While changes in mRNA decay rates account for approximately 50% of the regulation of gene expression in the cell, an assay to accurately and reliably measure mRNA half lives is currently not available. In particular, the deficiency of reliable commercial kits… More

Small RNA Barcoded Sequencing

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: HHS
Principal Investigator: Masoud Toloue – 512-707-8993
Award Amount: $235,725.00
Abstract:
DESCRIPTION (provided by applicant): Changes in expression have been shown to be associated with a variety of normal physiological processes as well as diseases including cancer. Studies have already shown that miRNAs may provide useful markers for the development of disease diagnostic and… More

Enzymatic Detection of Petroleum in Seafood

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: HHS
Principal Investigator: Joseph F. Krebs – 512-651-0200
Award Amount: $150,000.00
Abstract:
DESCRIPTION (provided by applicant): Oil spills can cause tremendous environmental damage and are a serious threat to public health. Petroleum contains many toxic compounds such as polyaromatic hydrocarbons (PAHs). Some PAH compounds are highly carcinogenic and cause DNA mutations in humans. When… More

SBIR Phase II: Biomolecular Detection of microRNA

Award Year / Program / Phase: 2012 / SBIR / Phase II
Agency: NSF
Principal Investigator: Masoud Toloue
Award Amount: $500,000.00
Abstract:
This Small Business Innovation Research Phase II project examines high throughput methods to quantify intacellular microRNA (miRNA) concentrations in cells that have shown to be associated with normal physiological processes, as well as diseases, including cancer. Currently there are no rapid,… More

Small Molecule Antiviral Agents Against Flaviviruses

Award Year / Program / Phase: 2012 / SBIR / Phase I
Agency: DOD
Principal Investigator: Joseph Krebs, Director – (512) 707-8993
Award Amount: $100,000.00
Abstract:
Flaviviruses are a major health threat worldwide. This family of RNA viruses causes a variety of deadly diseases such as Dengue Fever, Yellow Fever, West Nile virus, and Tick-borne Encephalitis. There are currently no effective means to control these viruses. New drugs to counteract these viruses… More

SBIR Phase I: Amplification-Free Small RNA Sequencing

Award Year / Program / Phase: 2013 / SBIR / Phase I
Agency: NSF
Principal Investigator: Masoud Toloue
Award Amount: $150,000.00
Abstract:
This Small Business Innovation Research (SBIR) Phase I project aims to make next generation sequencing technology for small RNA more quantitative and less biased. High throughput sequencing has transformed the landscape of genomic research with its ability to produce gigabases of data in a single… More